DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2812 and nmtn-1

DIOPT Version :10

Sequence 1:NP_611850.1 Gene:CG2812 / 37801 FlyBaseID:FBgn0034931 Length:348 Species:Drosophila melanogaster
Sequence 2:NP_491864.2 Gene:nmtn-1 / 172355 WormBaseID:WBGene00019434 Length:942 Species:Caenorhabditis elegans


Alignment Length:347 Identity:170/347 - (48%)
Similarity:229/347 - (65%) Gaps:19/347 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 VERP---------HFEAVTTLSDSQAIRSVDFHPNGKLYAVGSNSKTFRICQYPALSKLRHGHQA 70
            ::||         .|..|....||||||:..|||:|:.:|:|:|||...||.||...:.:....|
 Worm   598 LQRPVSAPTGMGVQFVPVCRYEDSQAIRATGFHPSGRYFALGTNSKQLHICLYPDTKRTQSRPMA 662

  Fly    71 AVYPPS----VLCKRTKHHRGSIYCTCWSRDGELIATGSNDKTIKYMRFNNDTNQLVGHEMELNM 131
              |..:    :...|.|.||||:||..::.:|:|:|||||||||:.|.||.|:.: :|.||||..
 Worm   663 --YEQTKNAEIAVTRPKQHRGSVYCLSFNPNGDLLATGSNDKTIRLMAFNEDSCR-IGAEMELTC 724

  Fly   132 HDGTVRDMCFLDDSSTKSRLLASGGAGDCKIYITDCGTGTPFQAYSGHTGHILSLYSWNNA--MF 194
            |||||||:.|::.|..:|.:|.|||||:|.:.:|||.||...|:..|||..||.||:|:.|  .|
 Worm   725 HDGTVRDLIFIESSINRSTILVSGGAGNCHLNVTDCNTGQLIQSMKGHTAPILGLYTWSQAGNQF 789

  Fly   195 VSGSQDQTIRFWDLRVNVSVNTLDNDRKDGGLESSAVTAVCVDPTGRLLVSGHADSSCTLYDIRG 259
            ||.|||:||||||||...:||.: :...:....:|.||:|||||.|:||||||.|:|..|:||.|
 Worm   790 VSCSQDKTIRFWDLRQQTAVNVI-SPGSNKSHNASPVTSVCVDPNGKLLVSGHEDASVALFDIGG 853

  Fly   260 NRPIQRFYPHTAEIRCVRFSPSAYYMLTCSYDNSIRLTDLQGDLAHELSSVVVAEHKDKAITIRW 324
            ||.:|.|.||..|:|.||||.:|||:||.|||..:.::|::|||...|..:.||||.||.:..||
 Worm   854 NRILQTFRPHGDEVRTVRFSNAAYYLLTASYDKRVVISDMRGDLMAPLMYLPVAEHSDKVVQCRW 918

  Fly   325 HPTEFSFISTSADKTATLWALP 346
            ||.:|||:|||||::|.||:||
 Worm   919 HPHDFSFLSTSADRSAVLWSLP 940

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2812NP_611850.1 WD40 <5..346 CDD:441893 168/345 (49%)
WD40 repeat 34..84 CDD:293791 16/53 (30%)
WD40 repeat 90..131 CDD:293791 22/40 (55%)
WD40 repeat 136..177 CDD:293791 19/40 (48%)
WD40 repeat 185..218 CDD:293791 20/34 (59%)
WD40 repeat 231..267 CDD:293791 23/35 (66%)
WD40 repeat 273..312 CDD:293791 18/38 (47%)
WD40 repeat 319..343 CDD:293791 13/23 (57%)
nmtn-1NP_491864.2 CTLH 62..118 CDD:128914
WD40 <621..941 CDD:441893 165/324 (51%)
WD40 repeat 629..678 CDD:293791 16/50 (32%)
WD40 repeat 683..724 CDD:293791 22/41 (54%)
WD40 repeat 730..771 CDD:293791 18/40 (45%)
WD40 repeat 776..818 CDD:293791 22/42 (52%)
WD40 repeat 826..861 CDD:293791 22/34 (65%)
WD40 repeat 867..905 CDD:293791 18/37 (49%)
WD40 repeat 913..939 CDD:293791 15/25 (60%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.