Protein Alignment kcc and LOC5667478

DIOPT Version :10

• Sequence 1: NP_001286795.1
• Gene: kcc / 37800
• FlyBaseID: FBgn0261794
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: XP_001687817.2
• Gene: LOC5667478 / 5667478
• VectorBaseID: AGAMI1_005795
• Length: 998
• Species: Anopheles gambiae
• Alignment Length: 1197
• Identity: 283/1197 - (23%)
• Similarity: 488/1197 - (40%)
• Gaps: 335/1197 - (27%)

  Fly     4 NSAKDDSDEMEIIPSEH-NGTVHETK----NEDSGDIHRAEENQKSSIDPNLYLYDDDLETRPHI 63
            |.|...|||..::...: ||.:|...    :|....:.....:|:::..|::.:...|.:::
Mosquito    14 NPAVVVSDESVVLEMNNGNGRIHRDSLLGLSEPLPRLDHYRASQRNAKRPSIGVLHGDRDSK--- 75

  Fly    64 STFISSIANYENTIPAATDP------DAKPAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVG 122
                           |..:|      :||....:.|:|.:.||.:||:.||:||:||:||:||||
Mosquito    76 ---------------AGGEPEELLEEEAKAPGHAIRLGWVQGVLIPCLLNIWGVMLFLRLSWVVG 125

  Fly   123 TAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTL 187
            .||.|...:|:.....|.::|.:|:||:.|||.:.:||.|::||||||.|||.:||::|....::
Mosquito   126 QAGIVQTLIIIALSYVVCVMTTLSLSALCTNGQIKSGGLYYIISRSLGAEFGASVGIVFAFANSV 190

  Fly   188 AAAMYIVGAVEIVLTYMAPWASIFGDF-----TKDADAMYNNFRVYGTLLLIFMGLIVFLGVKFV 247
            .|||..:|           :.|...|.     ||..|...|:.|:.|:..|:.|.:|..:|:.:.
Mosquito   191 NAAMNTIG-----------FCSSLNDLLRSLNTKIVDGGVNDIRIVGSAFLLLMIIICAVGMDWE 244

  Fly   248 NKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKEDSFLRDIYCPDG 312
            .|.....|..::::|....:|             .::|                        |..
Mosquito   245 VKAQNFLLVLIVVAIFNFIIG-------------AIVG------------------------PGA 272

  Fly   313 KCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFISYGKSAIDIENTSGESYNQIMADIT 377
            ..||.        .||..|:::.:...|:.|.:                         .:|..:.
Mosquito   273 SSEEL--------GKGFLGISATLLAANMGPGY-------------------------TVMNGVQ 304

  Fly   378 TSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLL 442
            .:|..:..|||||||||.:|:|..|||.|..|:||.||:.|.|.::..|:...:..||..    :
Mosquito   305 QNFFSVFAIFFPSVTGIQSGANICGDLRDPAKAIPKGTLWACLISAISYVLFSLMAAGAA----V 365

  Fly   443 RDKFGQS---IG---GKLVVANIAWP--NQWVIL-----------IGSFLSTLGAGLQSLTGAPR 488
            |:..|.:   :|   ......|..:.  |.:.::           .|.:.:||...|.::...||
Mosquito   366 REASGNASDLVGVTFTSCAAGNCTYGLLNDYTVMQLISLTSAITYAGCWAATLSTALTNILSVPR 430

  Fly   489 LLQAIARDEIIPFLAPFAKS-SKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFV 552
            |:||:..|.|.|.|..|:|. .|.|||.|...|..::....||:.::|.:|.|::..:|..|.|:
Mosquito   431 LIQALGIDRIYPGLIFFSKGYGKHGEPYRGYGLVFLVSLIFILIADLDAIASLITNLYLASYAFI 495

  Fly   553 NLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGA 617
            |........::...|||.|::||..:||:...||:::|.:.|...:.|||....::|..:.||..
Mosquito   496 NFCTFHAATVKPLGWRPTFRYYHPYVSLLATVLCVAIMFLISVVSSFIAMAFIFVLYLVVVYRKP 560

  Fly   618 EKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYR-KIFSFATQLKAG 681
            |..||..::..|...|..|.|.||....|.||::||||.::  .|   |..| .:...|..:...
Mosquito   561 EANWGSSVQAQAYKTALNSTLNLEGTSDHVKNYQPQILAIA--GD---PMQRPALIDLAHLITKH 620

  Fly   682 KGLTICVSVIKGDHTKITNKAVDAKATLRK-YMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGG 745
            ..|.:..::|.   .::..|...|.:.:.| |:.|..::.|..::......:|...:||:.|.|.
Mosquito   621 SSLMVIGNIIP---QRLPYKRRRALSDMGKSYLKDSNIRAFYKIVDGVDFDQGARCLIQSTGFGR 682

  Fly   746 MKPNTVIIGWPYSWRQEGRNSWKTFIQTVRTVAACHMALMV---PKGINFY-------------- 793
            :.||.:::|:..:||.........:..|:.|.....:||::   .||::.:
Mosquito   683 LAPNILMLGYKTNWRAANHQQLNAYYNTLHTAFDNRLALLILRMGKGLDIFKGLSSSDLYTTVPS 747

  Fly   794 ---------------------------------------------------------------PE 795
                                                                           ||
Mosquito   748 PQETTVSFTSKRMAARRSLMPVNSNLDLHELMQSNRSSQTSPAPTFHAAPAFDYPSPPVVPAEPE 812

  Fly   796 SN----HKIGGNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTF 856
            :|    .:..|.||:||:..||||.||||:::.....|..||:|:|.::.:  |..:.:.:||..
Mosquito   813 ANLFKQKQPKGTIDVWWLYDDGGLTMLLPYIITTRSKWEKCKIRVFALSSV--NVQEEETNLKLL 875

  Fly   857 LYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYKETPSDN 921
            |..|||               :|.               :|.:.|..:..:..||.:::
Mosquito   876 LDKLRI---------------SYL---------------SLTMVKVTDKPMESTIEEHR------ 904

  Fly   922 KMSLVQTIVDHHYDATKTASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDE 986
              :|::|:.|.:.|.           |.:.|:        ||:..            |..:|:.
Mosquito   905 --ALLRTVADTNDDL-----------PVLSES--------EKQQL------------EVKTNRQ- 935

  Fly   987 STEKADGDFKSSVKPDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPRE-VRAERERNYME 1050
                                      ::|.|:::|.|:.|.|::|::|.|.:: |.|..   ||.
Mosquito   936 --------------------------LRLRELLLEHSKSASLIVMSMPVPRQDTVSAVL---YMS 971

  Fly  1051 FLEVLTEGLEKVLMVRGGGREVITIYS 1077
            :||:||:.:...|:|||...||:|.||
Mosquito   972 WLEMLTKDMPPFLLVRGNQTEVLTFYS 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcc	NP_001286795.1	AA_permease_2	49..1077	CDD:459263	270/1145 (24%)
LOC5667478	XP_001687817.2	AA_permease_2	45..998	CDD:459263	273/1164 (23%)