Protein Alignment kcc and CG12773

DIOPT Version :10

• Sequence 1: NP_001286795.1
• Gene: kcc / 37800
• FlyBaseID: FBgn0261794
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_569905.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Alignment Length: 748
• Identity: 162/748 - (21%)
• Similarity: 269/748 - (35%)
• Gaps: 275/748 - (36%)

  Fly    18 SEHNG-----TVHETK----NEDSGDI------HRAEENQKSSID-PNLYLYDDDLETRPHISTF 66
            ||.||     ||...:    .::.||:      .|...|....:| .|.|.|...
  Fly     5 SEGNGNGGRRTVDWQRFGLGGDEDGDVAVTSFRQRTNNNTGGFVDLGNEYTYAAG---------- 59

  Fly    67 ISSIANYENTIPAATDPDAKP-------AAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTA 124
             ...|:..|.|.|....| ||       .:.....||..|||..|:.|:||||:|:|..|:|..|
  Fly    60 -GHHASGANEIFAGEQGD-KPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQA 122

  Fly   125 GAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAA 189
            |.:...||:.....:.:::.:|...|.....|.:||.||:|:.:||..||||:|:|:..|..:..
  Fly   123 GILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGC 187

  Fly   190 AMYIVGAVE----IVLTYMAPWASIFGDFTKDADAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKF 250
            |:.::|..|    :|....:.||                .|.:.|..::.:|.|...|||:|.|.
  Fly   188 ALNVMGFGESMAGLVGLEGSKWA----------------IRGFATAAVLLLGCINVAGVKWVIKL 236

  Fly   251 ATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKEDSFLRDIYCPDGKCE 315
            ..:.|..:::|.:...||.|                           |.|.|
  Fly   237 QFILLMILLISALDFMVGSF---------------------------TSEAS------------- 261

  Fly   316 EYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFISYGKSAIDIENTSGESYNQIMADITTSF 380
                       .|..|.|||.|.:|::|.:                             |...|:
  Fly   262 -----------GGFNGWASGNFVENLWPKY-----------------------------DDGYSW 286

  Fly   381 TLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDK 445
            ..:.|:|||:|||:::|.|.||||......||.||:.|..|::.:||..|:|...|.....|...
  Fly   287 FRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTD 351

  Fly   446 FGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSK 510
            :..|:....|        .:::|.|.::|::.:.|.::.|.||:||:||::.:||.:....|.
  Fly   352 YMISVKVSAV--------HFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKG-- 406

  Fly   511 RGE---PTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLA----------------- 555
            ||.   |..|:.:..::....|::|:::.|||:::|.||:.|..::.|
  Fly   407 RGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREER 471

  Fly   556 ----------------------------------------------------------------- 555
                                                                             
  Fly   472 FRIQASSPSYETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQA 536

  Fly   556 --------------CAVQTLL-------------------------RTPNWRPRFKFY--HWSLS 579
                          .||:..:                         :|.||   :..|  .|: |
  Fly   537 QSSERRTGHEADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTKNW---YSGYCNRWA-S 597

  Fly   580 LIGLTLCISVMIMTSWYFALIAMGMAIIIYKYI 612
            |:|....:.||::.:||:||....:..:::.|:
  Fly   598 LLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYV 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcc	NP_001286795.1	AA_permease_2	49..1077	CDD:459263	151/701 (22%)
CG12773	NP_569905.1	AA_permease_2	88..>456	CDD:459263	124/473 (26%)