Protein Alignment kcc and B0303.11

DIOPT Version :9

• Sequence 1: NP_001286795.1
• Gene: kcc / 37800
• FlyBaseID: FBgn0261794
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: NP_001299855.1
• Gene: B0303.11 / 176222
• WormBaseID: WBGene00015131
• Length: 927
• Species: Caenorhabditis elegans
• Alignment Length: 1128
• Identity: 223/1128 - (19%)
• Similarity: 372/1128 - (32%)
• Gaps: 359/1128 - (31%)

  Fly    80 ATDPDAKPAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTA 144
            |:..|| |...:|.|... .|||.|:|.:..|:|.:|.:.:|..||.....::|.....|:::|.
 Worm     6 ASSEDA-PITSTAWMNWK-DVFLKCVQPMLAVVLLLRFSSIVDEAGFTTTIILVFFTFLVSLVTG 68

  Fly   145 ISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWAS 209
            .|...:.:......|....|::.| ..||..:..:::.....:|.:.::..|.|.||       .
 Worm    69 WSACTVVSRKSSEVGFVKTMLAYS-STEFAISFSIIYLFCLLVATSTFLTSAAEAVL-------H 125

  Fly   210 IFGDFTKD-ADAMYNNFRVYGTLL-LIFMGLIVF--LGVKFVNKFATVALACVILSIIAVYVGIF 270
            ||..|:.: .|...::.|:..::| ||.:.|.:.  ...:||..| ..||.|:   .||:.:...
 Worm   126 IFSTFSLELLDGATHDLRLVSSVLSLITLALCMVRNRNARFVRTF-IFALTCI---AIALQLSSV 186

  Fly   271 DNIHGNEKLYMCVLGKRLLKDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASG 335
            ...:|..:|       |.:.|             |:...|....||
 Worm   187 MFRYGEYQL-------RRVSD-------------RNAMIPSPPNEE------------------- 212

  Fly   336 VFYDNIFPSFLEKGQFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNR 400
                                                    |:|.|..|.......:|.:..||.
 Worm   213 ----------------------------------------ISTIFAQLFPAAMCGLTILNIGSK- 236

  Fly   401 SGDLADAQKSIPIGTICAILTTSTVY-----LSSVMFFAGTVDNLLLRDKFGQSIGGK-----LV 455
                  .|.:.|.|.:.||..::..|     |..|.|||        |.....|.|..     |.
 Worm   237 ------LQNTAPRGALIAIAVSACFYGAAAMLDYVEFFA--------RTSTSNSTGSAEYNEFLS 287

  Fly   456 VANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKS-SKRGEPTRALL 519
            ......|...||.:...||    .:.:|..|..:||::.|......:...||. .:|..|.|.||
 Worm   288 YIYTTVPMAIVITLACVLS----AVSTLKYAAVILQSLGRSNQCRCILWLAKGFGERDIPIRCLL 348

  Fly   520 LTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLT 584
            |...:......:|:.|:|....::|:|..|...|....:..|.     .|........|||....
 Worm   349 LLSTVQILVSAIGSYDILCIPTTVFYLFAYALFNFYVFLVKLS-----DPEIPSPPTLLSLAISA 408

  Fly   585 LCISVMIMTSWYFALIAMGMAIIIYKYIEY--RGAEKEWGDGIRGMALTAARYSLLRLEEGPPHT 647
            .|....:.|:.:.||....:..|.|..:.|  |....|.|:.......::....:..|::.|...
 Worm   409 ACFIASLYTNRHLALFIASIFAISYCSLLYIIRRERNEDGEECPKSMYSSVLEQMHELQQEPDSR 473

  Fly   648 KNWRPQILVLSKLNDNLLPKYRK-IFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRK 711
            :::.||||:||.     .|..|. :..||..:..||.|.||..:|    .||:|| |:...|..:
 Worm   474 RHFHPQILLLSG-----SPAARPGLVDFAHSITRGKSLLICGYII----PKISNK-VEQPMTWTE 528

  Fly   712 YMTDE------------------------KVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVI 752
            |:..:                        :|..|...:...:..||.:.::||.|||.::||.::
 Worm   529 YLMQQSPCSRSYLLQLKIDKQINDWLRAREVNAFGAAICCTKQAEGANILLQTAGLGRLRPNILM 593

  Fly   753 IGWPYSWRQEGRNSWKTFIQTVRTVAACHMALM-------------------------------- 785
            :|:...|.:..:.|...:...:.......:.::
 Worm   594 LGYKTGWEKLSKESISEYYGMLSNAFDKQVGVIIFRNEASGFDVTSSIRKNGAPINDDEDLAEYV 658

  Fly   786 ----------------VPKG--INFY---------------------------------PESNHK 799
                            ||:|  :|.:                                 .|.:.|
 Worm   659 DSATPKLADQGSQKKDVPRGKLLNTFRKMSMAVNKDLESGGRRSTSSSTRFQVIDKHSISEPDQK 723

  Fly   800 I-------------GGNIDIWWIVHDGGLLMLLPFLLKQHRTW-RNCKLRIFTVAQIEDNSIQMK 850
            |             ...||::|:...|||.||.|:||.|..:: ....:|:||....:||
 Worm   724 IIMAQMFRFRKRIPNARIDVFWLREAGGLTMLAPYLLTQAGSFLEGAHIRVFTKTDGKDN----- 783

  Fly   851 KDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYK 915
                                            :.:..||:|.   |..|.|
 Worm   784 --------------------------------KRINEEQKNM---AAILRK-------------- 799

  Fly   916 ETPSDNKMSLVQTIVDHHYDATKTASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPET 980
                            .|.|::.......|:.|..::|.      ||.|..||      ....||
 Worm   800 ----------------FHIDSSDLHILPEFSKPPCKQTY------DEFRAKID------KYKVET 836

  Fly   981 TSNKDESTEKADGDFKSSVKPDEFNVR-RMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAER 1044
            :|    |.|..||.|.::   ..||:| :..:.::.:|:|.|.|.||.|::..||....|:.:.
 Worm   837 SS----SGEPVDGSFDNN---QIFNLREKTRSFLRASELIREHSSDADLIVCTLPSARPEIPSP- 893

  Fly  1045 ERNYMEFLEVLTEGLEKVLMVRG 1067
              .|:.::::|:.......:|||
 Worm   894 --IYLGWIDMLSRQTPPTCLVRG 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcc	NP_001286795.1	2a30	49..1077	CDD:273347	223/1128 (20%)
		SLC12	674..1077	CDD:281515	95/516 (18%)
B0303.11	NP_001299855.1	2a30	2..916	CDD:273347	223/1128 (20%)
		SLC12	490..919	CDD:397542	96/522 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810