Protein Alignment kcc and Ncc69

DIOPT Version :10

• Sequence 1: NP_001286795.1
• Gene: kcc / 37800
• FlyBaseID: FBgn0261794
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: XP_061499156.1
• Gene: Ncc69 / 1281611
• VectorBaseID: AGAMI1_005952
• Length: 1141
• Species: Anopheles gambiae
• Alignment Length: 1247
• Identity: 314/1247 - (25%)
• Similarity: 492/1247 - (39%)
• Gaps: 383/1247 - (30%)

  Fly     2 QSNSAKDDSDEM---------------EIIPSEHNGTVHETKNEDSGDIHRAEENQKSSIDPNLY 51
            :|:|..|:.|.:               |.:|          :.::..:|...:.||:.::|.
Mosquito   107 ESDSNDDEEDNLIDENRYARSFRHFTREALP----------RMDNYRNILSFQGNQRPTLDE--- 158

  Fly    52 LYDDDLETRPHISTFISSIANYENTIPAATDPDAKPAAPSARMGTLIGVFLPCIQNIFGVILFIR 116
            |:|             :||.|.| |:...|..:......|.:.|.:.||.:.|:.||:||:||:|
Mosquito   159 LHD-------------ASITNKE-TMRRGTVHEPAELDGSIKFGWIKGVLMRCLLNIWGVMLFLR 209

  Fly   117 LTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLF 181
            |:||||.||.|.|.:::.....||.:||:|||||:||||:..||:|:||||||||||||::|::|
Mosquito   210 LSWVVGQAGIVQGVVLICMTTVVTTITALSMSAISTNGVIKGGGTYYMISRSLGPEFGGSIGLIF 274

  Fly   182 YTGTTLAAAMYIVGAVEIVLTYMAPWASIFGDFTKDADAMYNNFRVYGTLLLIFMGLIVFLGVKF 246
            .....:|.|||:||..|.::..:|.    ||  ....|...|:.|:.|.:.::.:..||.:|:::
Mosquito   275 SLANAVACAMYVVGFCESMIDLLAS----FG--VAIVDGAVNDVRIIGCITIVLLLCIVVVGMEW 333

  Fly   247 VNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKEDSFLRDIYCPD 311
            ..|...|.|..::::|:...||                                     .::.|.
Mosquito   334 EAKAQIVLLIILLVAIVDFCVG-------------------------------------SLWGPK 361

  Fly   312 GKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFISYGKSAIDIENTSGESYNQIMADI 376
            .:.:                :|.|               |:.|..:.: :||.  :|..::....
Mosquito   362 SELD----------------VARG---------------FVGYNATVL-MENM--QSAYRVSKGT 392

  Fly   377 TTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLL 441
            ...|..:..||||:.|||:||:|.||||.|...|||.|||.||..||..|:...:....||
Mosquito   393 QHDFFSVFSIFFPAATGILAGANISGDLKDPSSSIPKGTILAIAITSASYIGMAVMAGATV---- 453

  Fly   442 LRDKFGQSIGGKLVVANIAWP--------------NQW-----------VILIGSFLSTLGAGLQ 481
            |||    :.|....|.|..|.              |.:           :|..|.|.:||.:.|.
Mosquito   454 LRD----ATGNVTDVVNGTWDFSACEETSCAYGLHNSFQVMELVSVFGPLIYAGCFAATLSSALA 514

  Fly   482 SLTGAPRLLQAIARDEIIPFLAPFAKS-SKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFF 545
            ||..||::.||:.:|::.|.::.|.|. .|..||.|..:||.||....||:|:::::|||:|.||
Mosquito   515 SLVSAPKVFQALCKDKLYPKISWFGKGFGKNNEPVRGYILTFVISVAVILVGDLNMIAPLISNFF 579

  Fly   546 LMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYK 610
            |..|..||.:....:|.:...|||.||:|:..|||:|...||:||.:.||..|||.....:.:|.
Mosquito   580 LAAYCLVNFSTFHASLAKPVGWRPTFKYYNMWLSLLGAIFCIAVMFLISWPTALITFAAVLSLYL 644

  Fly   611 YIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIF-SF 674
            .:.||..:..||...:......|..|:.:|.....|.||:|||||||..     .|..|.:. :|
Mosquito   645 IVSYRKPDVNWGSTTQAQTYKNALLSVQQLNNVEEHVKNYRPQILVLCG-----HPSSRPLLVNF 704

  Fly   675 ATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQ 739
            |..|.....|.:|..|.|...::.....:..||.  ::....|||||..::.......|..:::|
Mosquito   705 AYLLTKKLSLLVCGHVTKTHVSQKYRNHLQKKAA--EWFRRHKVKGFYSLIDDNDFETGSRAIMQ 767

  Fly   740 TIGLGGMKPNTVIIGWPYSWRQEGRNSWKTFIQTVRTVAACHMA---LMVPKGINF--------- 792
            ..|:|.::||.:::|:...|.:......:.:...|......:::   |.|.||.::
Mosquito   768 ASGIGKLRPNVLLMGFKSDWDRCEPAELEQYFNVVHKALDMYLSVAILRVGKGFDYSQVLGEDTV 832

  Fly   793 -----YPE------------SNHKIG--------------------------------------- 801
                 ||.            |::|:.
Mosquito   833 KFISEYPRTLVANDSTNDLLSHNKVSSLHGSCDSLSRNVSQDQTNDVNEKNAKNLKASSTSDLSK 897

  Fly   802 ----------------------------------------------------------GNIDIWW 808
                                                                      |.||::|
Mosquito   898 TISVAPDPIDINAKLITETGQRSLKRGDPSLLYRGPGGAELPTEVLDELTQFTSKKKTGIIDVYW 962

  Fly   809 IVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNN 873
            :..||||.:|||:::...|.|.:||||:|.:|           :.||
Mosquito   963 LYDDGGLTLLLPYIISTRRNWASCKLRVFALA-----------NRKT------------------ 998

  Fly   874 SDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYKETPSDNKMSLVQTIVDHHYDATK 938
                      .|..||||..           |.:.:..:||.:      :.|:.       |.||
Mosquito   999 ----------ELEFEQRNMA-----------SLLAKFRIDYSD------LQLLP-------DVTK 1029

  Fly   939 TASK--VRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPET-TSNKDESTEKADGDFKSSVK 1000
            ..::  ..|....|:|....|...|             |.|..| |.:|.|.....|
Mosquito  1030 KPNQEMADFFKGLIKEFTAKDDAAD-------------ASTAGTSTISKAELLAVQD-------- 1073

  Fly  1001 PDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMV 1065
                   :.:..:.|.|.:::.|..:.||:|.||.|.:.|.:  ...||.:||.|:..|...|.|
Mosquito  1074 -------KTNRHLNLREYLLQHSSKSDLVVMTLPMPRKGVVS--APLYMAWLEALSRDLPPFLFV 1129

  Fly  1066 RGGGREVITIYS 1077
            ||....|:|.||
Mosquito  1130 RGNQTSVLTFYS 1141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcc	NP_001286795.1	AA_permease_2	49..1077	CDD:459263	302/1183 (26%)
Ncc69	XP_061499156.1	None