Protein Alignment kcc and LOC1269177

DIOPT Version :10

• Sequence 1: NP_001286795.1
• Gene: kcc / 37800
• FlyBaseID: FBgn0261794
• Length: 1077
• Species: Drosophila melanogaster
• Sequence 2: XP_560491.5
• Gene: LOC1269177 / 1269177
• VectorBaseID: AGAMI1_006553
• Length: 1064
• Species: Anopheles gambiae
• Alignment Length: 1179
• Identity: 290/1179 - (24%)
• Similarity: 471/1179 - (39%)
• Gaps: 317/1179 - (26%)

  Fly    31 DSGDIHRAEENQKSSIDPNLYLYDDDLETRPHISTFIS-----SIANYENTIPAATDPDAK---- 86
            :||...|......|:.|.:.:|..|.|....|..|...     ||......:. ..|.||.
Mosquito    71 ESGYDDRTANGADSAHDADHHLTTDPLPRLEHYRTSQKVIRRPSIGELHGDLD-EQDTDANDRND 134

  Fly    87 -----PAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAIS 146
                 |.....|:|.:.||.:||:.||:||:||:||:|||..||.:...||:.....|.::|.:|
Mosquito   135 SCQTGPDHAGIRLGWVQGVLIPCLLNIWGVMLFLRLSWVVALAGILETLLIIGLSYLVCVITTLS 199

  Fly   147 MSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIF 211
            :||:.|||.|..||.|::||||||||||||||::.....:::|:|..:|....:...:|.    |
Mosquito   200 LSAMCTNGQVKGGGIYYLISRSLGPEFGGAVGIVLAFSNSVSASMNTIGFCSSLNQLLAS----F 260

  Fly   212 GDFTKDADAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGN 276
            |  .|..|...|:.|:.|||.::.|.||..:|:.:..|...|.:..::|:|....||:
Mosquito   261 G--VKIFDGGVNDMRLVGTLTILLMVLICAVGMDWEAKAQNVLVVAIVLAIGGFTVGV------- 316

  Fly   277 EKLYMCVLGKRLLKDIPLENCTKEDSFLRDIYCPDGKCEEYYLANNVTKVKGIKGLASGVFYDNI 341
                  :||.|                                 .:..:.||..||:...|.||:
Mosquito   317 ------LLGPR---------------------------------TDTDRAKGFTGLSGERFVDNL 342

  Fly   342 FPSFLEKGQFISYGKSAIDIENTSGESYNQIMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLAD 406
            .|                |..::.|         |...|..:.|||||||||:.||:|..|:|.|
Mosquito   343 GP----------------DYRHSEG---------IEQDFFSVFGIFFPSVTGVQAGANICGELKD 382

  Fly   407 AQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNL--------LLRDKFGQSIGGKLVVANIAWPN 463
            ...:||.||:.|:|.:...|::.|: .||:....        |:...||:...|..........|
Mosquito   383 PATAIPKGTLLALLISGLSYVAFVL-LAGSASYRDASGDLADLVNGTFGRCSSGPQEPCRYGLHN 446

  Fly   464 QW-----------VILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKS-SKRGEPTR 516
            .:           :|..|.|.:||...|.:||..||::||:..|.:.|.|..||:. .||.||.|
Mosquito   447 DYNIMQLMAVSGALIYAGCFAATLSTALTNLTSVPRIIQALGTDRLYPGLTYFAQGFGKRNEPYR 511

  Fly   517 ALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLI 581
            :..|.:.:....:||.|::|||||::.|:|..|..:|........::...|||.|::|:..:||:
Mosquito   512 SYALVLCVSVLFVLLANLNLLAPLITNFYLASYALINFCTFHAATVKPIGWRPTFRYYNQWVSLL 576

  Fly   582 GLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPH 646
            |..||:.:|.:.......:.|.:..:::..:.||..:..||...:..:..:|..:.|:|:....|
Mosquito   577 GTVLCVLIMFLIDIISTGVTMVLIFVLHLAVIYRKPDVNWGSTTQAQSYKSALSAALKLQCVGDH 641

  Fly   647 TKNWRPQILVLSKLNDNLLPKYR-KIFSFATQLKAGKGLTICVSVIKG--DHTKITNKAVDAKAT 708
            .||:.|.:|||:.     .|..| .:...|.|:...:.|.|...|::.  .|.|...::.|.
Mosquito   642 VKNYHPSVLVLTG-----QPATRPALIELAHQITKRQALLIVGDVVRDRLSHRKRELRSRDC--- 698

  Fly   709 LRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQEGRNSWKTFIQT 773
             |.:|...|::||..::....:.:|:.::|||.|:|.:..|.|::|:...|.:.......|:...
Mosquito   699 -RSFMELRKIEGFYQLIDGIGLEKGVRALIQTSGVGKLSANIVLVGYKADWMRCPVQELHTYYNV 762

  Fly   774 VRTVAACHMALMV---PKGIN-------------------------------------------- 791
            :..|....|:|.|   |.|::
Mosquito   763 LNDVFDNRMSLAVLRLPNGLDLSYLTSDGPSNTGGSLGTIANDSLSSLQQHIIDASAAHQTTNKL 827

  Fly   792 FYPESN------HKIG----------------------------------------GNIDIWWIV 810
            .|.:||      .|:|                                        |.||:||:.
Mosquito   828 MYVDSNLGFQGAGKVGRTESPSNTSRESIACSTRAESCLPLELHDRLNVFRHKQPKGTIDVWWLY 892

  Fly   811 HDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSD 875
            .||||.||:|::|.....|.:||:|:|.:.
Mosquito   893 DDGGLTMLIPYILSMRSKWADCKVRVFALT----------------------------------- 922

  Fly   876 ISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMDYKETPSDNKMSLVQTIVD--HHYDATK 938
                ..:|.|.:||:| |...|...:.:.|.::. :.|..:.|....:.|.|.::.  .|..|..
Mosquito   923 ----NQQRELELEQKN-MANLLAKLRIDYSSLIM-LQDVTQPPRPETVQLHQQLLKSFDHLPAHL 981

  Fly   939 TASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADGDFKSSVKPDE 1003
            |..                          :|..||.....|.|
Mosquito   982 TPP--------------------------ELSSPERVALAEKT---------------------- 998

  Fly  1004 FNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGG 1068
                  |..::|.|:::|.|.:|:|::|::|.|  .:.......||.:||:|::.:..:|:|||.
Mosquito   999 ------HRQLRLREMLLEHSLEARLIVMSMPMP--RMGTVSASLYMSWLEMLSKDMPPMLLVRGN 1055

  Fly  1069 GREVITIYS 1077
            ...|:|.||
Mosquito  1056 QTSVLTFYS 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcc	NP_001286795.1	AA_permease_2	49..1077	CDD:459263	283/1159 (24%)
LOC1269177	XP_560491.5	None