DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nap1 and TSPYL1

DIOPT Version :9

Sequence 1:	NP_001246485.1	Gene:	Nap1 / 37798	FlyBaseID:	FBgn0015268	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_003300.1	Gene:	TSPYL1 / 7259	HGNCID:	12382	Length:	437	Species:	Homo sapiens

Alignment Length:	275	Identity:	56/275 - (20%)
Similarity:	103/275 - (37%)	Gaps:	88/275 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LEQKYQVQYQPLFDKRREIIEG---KVDPAEEKPQW-------KEPESSTDNEADA--------- 126
            :|::.:|:.||...:..|:.|.   :.:..||:..|       .:|..:...|.|.
Human   186 MEEQMEVEEQPPEGEEIEVAEEDRLEEEAREEEGPWPLHEALRMDPLEAIQLELDTVNAQADRAF 250

  Fly   127 -----------EHFREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISI 180
                       .|:.|..:.:      .:.|||||:|.|||...:|.|::..|...:|.:.::.:
Human   251 QQLEHKFGRMRRHYLERRNYI------IQNIPGFWMTAFRNHPQLSAMIRGQDAEMLRYITNLEV 309

  Fly   181 KYDNGHSYT---LEFHFDKNEYFSNSVLTKQYVLKST---VDPNDPFAFEGPEIYKCTGCTINWE 239
            | :..|..|   .:|.|.:|.||.|.::.|:|.::|:   |..:.|               |.|
Human   310 K-ELRHPRTGCKFKFFFRRNPYFRNKLIVKEYEVRSSGRVVSLSTP---------------IIW- 357

  Fly   240 KKMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVDDDSQQILATDFEIG 304
                        ::.|:.:..:|.  .|....|||.:||...:|...               :|.
Human   358 ------------RRGHEPQSFIRR--NQDLICSFFTWFSDHSLPESD---------------KIA 393

  Fly   305 HFLRARIIPKAVLYY 319
            ..::..:.|..:.||
Human   394 EIIKEDLWPNPLQYY 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nap1	NP_001246485.1	NAP	55..321	CDD:279323	56/275 (20%)
TSPYL1	NP_003300.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..81
TSPYL1	NP_003300.1	NAP	228..409	CDD:279323	47/233 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840