DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nap1 and SETSIP

DIOPT Version :10

Sequence 1:NP_477128.1 Gene:Nap1 / 37798 FlyBaseID:FBgn0015268 Length:370 Species:Drosophila melanogaster
Sequence 2:NP_001274666.2 Gene:SETSIP / 646817 HGNCID:42937 Length:292 Species:Homo sapiens


Alignment Length:331 Identity:80/331 - (24%)
Similarity:132/331 - (39%) Gaps:109/331 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 QNRIVFLKNLQLQHLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEPES 118
            |..|..:..:|.:...:..|..|::.|:||||....||.|.||.|:|                  
Human    42 QEAIEHIDEVQNEIDRLNEQDSEEILKVEQKYNKLRQPFFQKRSELI------------------ 88

  Fly   119 STDNEADAEHFREALSSLKSIPKDAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKL--IDISIK 181
                                    || ||.|.:|.|.|...:|.::...||.|:..|  ::::..
Human    89 ------------------------AK-IPNFGVTTFVNHPQVSSLLGEEDEEALHYLTKVEVTEF 128

  Fly   182 YDNGHSYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWE------K 240
            .|....|.::|:||:|.||.|.|.:|::.|..:.||:.          |.|  .|.|:      |
Human   129 EDIKSGYRIDFYFDENPYFENKVFSKEFHLNESGDPSS----------KST--KIKWKSGKDVTK 181

  Fly   241 KMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVD-DDSQQILATDFEIG 304
            :.:.|.....:|::|:|            .:|||.:|      :|..:.. |:.::::..|    
Human   182 RSSQTQNKASRKRQHEE------------PESFFTWF------TDHSDAGADELEEVIKDD---- 224

  Fly   305 HFLRARIIPKAVLYYTGDIVDDE-----DDEDEEEYDENEED------------EYDDDDAPPPK 352
                  |.|..:.||....:|||     ||:|:::.||.||:            |.|:||....:
Human   225 ------IWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEE 283

  Fly   353 GPKSAG 358
            |.:..|
Human   284 GEEDEG 289

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
Nap1NP_477128.1 NAP 55..322 CDD:460010 63/275 (23%)