Protein Alignment Nap1 and NAP1L4

DIOPT Version :10

• Sequence 1: NP_477128.1
• Gene: Nap1 / 37798
• FlyBaseID: FBgn0015268
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001356309.1
• Gene: NAP1L4 / 4676
• HGNCID: 7640
• Length: 386
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 173/386 - (44%)
• Similarity: 241/386 - (62%)
• Gaps: 42/386 - (10%)

  Fly    15 NEIEDEKSGSDCQSM-------PAYMNSVMRR-----QYLQQMVKMLPAPVQNRIVFLKNLQLQH 67
            :.:|..|:.|:.:.:       |..:.::..|     ......::.||..|:.||..||.||::.
Human    13 DSVEAAKNASNTEKLTDQVMQNPRVLAALQERLDNVPHTPSSYIETLPKAVKRRINALKQLQVRC 77

  Fly    68 LNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWKEPESSTDNEADAEHFREA 132
            .:|||:|:|:|:.||:||...||||||||||.|.|.|:|.:.:.:|     .::||.:.:...:.
Human    78 AHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESEW-----HSENEEEEKLAGDM 137

  Fly   133 LSSLKSIPK--------DAKGIPGFWLTVFRNTAIMSEMVQPHDEPAIRKLIDISIKY-DNGH-- 186
            .|.:....|        |.||||.||.|:|||..::||:||.:|||.::.|.||.:|: |.|.
Human   138 KSKVVVTEKAAATAEEPDPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPM 202

  Fly   187 SYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPNDPFAFEGPEIYKCTGCTINWEKKMNLTVKTIRK 251
            |:.|||||:.|:||:||||||.|.:||..|..|||:||||||..|.||||:|:|..|:|||||:|
Human   203 SFVLEFHFEPNDYFTNSVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKK 267

  Fly   252 KQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPSDQEEVDDDSQQILATDFEIGHFLRARIIPKAV 316
            |||||.||.||||.||||.:||||||:|.:...|.|.:|:||:..||:|||||||.|.||:|:||
Human   268 KQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAV 332

  Fly   317 LYYTGDIVDDED-----DEDEEEYDENEEDEYDDDDAP--PPKGPKSAGIKKQSPNDCPNQ 370
            ||:||:.::|:|     :|.|||..|.:|:..|:|||.  |.|.|       ..|.:|..|
Human   333 LYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDAEINPKKEP-------SQPAECKQQ 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nap1	NP_477128.1	NAP	55..322	CDD:460010	146/277 (53%)
NAP1L4	NP_001356309.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		3/17 (18%)
		NAP	65..338	CDD:460010	146/277 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..137		4/25 (16%)
		Nuclear localization signal. /evidence=ECO:0000255	265..271		4/5 (80%)