Protein Alignment Nap1 and NAP1L2

DIOPT Version :9

• Sequence 1: NP_001246485.1
• Gene: Nap1 / 37798
• FlyBaseID: FBgn0015268
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_068798.1
• Gene: NAP1L2 / 4674
• HGNCID: 7638
• Length: 460
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 131/389 - (33%)
• Similarity: 196/389 - (50%)
• Gaps: 84/389 - (21%)

  Fly    18 EDEKSGSDC---------QSMPAYMNSVMRRQYLQQMVKMLPAPVQNRIVFLKNLQLQHLNIEAQ 73
            ||.|.|.|.         :.:..|:...       ..|:.||..|:.|::.||.||.:..|:|::
Human    71 EDGKKGGDTDEDSEADRPKGLIGYVLDT-------DFVESLPVKVKYRVLALKKLQTRAANLESK 128

  Fly    74 FFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWK------------------------ 114
            |..:.:.:|:|:...||||.:|||:||....:|.||:.::|
Human   129 FLREFHDIERKFAEMYQPLLEKRRQIINAIYEPTEEECEYKSDSEDCDDEEMCHEEMYGNEEGMV 193

  Fly   115 -----------------------EPESSTDNEADAEHFREALSSLKSIPKDAKGIPGFWLTVFRN 156
                                   |.|...|.||..|..:|        .:|.||||.|||||.:|
Human   194 HEYVDEDDGYEDYYYDYAVEEEEEEEEEDDIEATGEENKE--------EEDPKGIPDFWLTVLKN 250

  Fly   157 TAIMSEMVQPHDEPAIRKLIDISIKY-DNGH--SYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPN 218
            ...::.:::.:|||.::.|.||.:|. |.|.  |:||||||..||||.|.:|||.|||||.:...
Human   251 VDTLTPLIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLAYY 315

  Fly   219 DPFAFEGPEIYKCTGCTINWEKKMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVP 283
            ||..:.|..|...|||.|:|.:..|:|:|||:|||||:..|.:||:.:..|.|||||||||..:.
Human   316 DPHPYRGTAIEYSTGCEIDWNEGKNVTLKTIKKKQKHRIWGTIRTVTEDFPKDSFFNFFSPHGIT 380

  Fly   284 SDQEEVDDDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDE--YDD 345
            |:..:.:|        ||.:||.||..|||::||:::||.::.:.:....|.::...|:  ||:
Human   381 SNGRDGND--------DFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDAIYDKIIYDN 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nap1	NP_001246485.1	NAP	55..321	CDD:279323	115/315 (37%)
NAP1L2	NP_068798.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..88		5/16 (31%)
		NAP	111..410	CDD:279323	115/314 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..238		8/31 (26%)
		Nuclear localization signal. /evidence=ECO:0000255	346..352		4/5 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152009
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1507
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53841
OrthoDB	1	1.010	-	-		D1216172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X426
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.820