DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nap1 and Nap1l2

DIOPT Version :9

Sequence 1:	NP_001246485.1	Gene:	Nap1 / 37798	FlyBaseID:	FBgn0015268	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_032697.2	Gene:	Nap1l2 / 17954	MGIID:	106654	Length:	460	Species:	Mus musculus

Alignment Length:	388	Identity:	130/388 - (33%)
Similarity:	200/388 - (51%)	Gaps:	59/388 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DAPAEGHVDPESCNEIEDEKSGSDCQSMPAYMNSVMRRQYLQQMVKMLPAPVQNRIVFLKNLQLQ 66
            :|.|....|...|...:::......:.:..|:...       ..|:.||..|:.|::.||.||.:
Mouse    64 EAAAGSGEDAGKCGGTDEDSDSDRPKGLIGYLLDT-------DFVESLPVKVKCRVLALKKLQTR 121

  Fly    67 HLNIEAQFFEDVYKLEQKYQVQYQPLFDKRREIIEGKVDPAEEKPQWK------------EPESS 119
            ..::|::|..:.:.:|:|:...||||.:|||:||....:|.||:.::|            |.|.:
Mouse   122 AAHLESKFLREFHDIERKFAEMYQPLLEKRRQIINAVYEPTEEECEYKSDCEDYFEEEMDEEEET 186

  Fly   120 TDNE---------------------ADAEHFRE------ALSSLKSIPKDAKGIPGFWLTVFRNT 157
            ..||                     .|.|...|      |....:...:|.||||.|||||.:|.
Mouse   187 NGNEDGMVHEYVDEDDGYEDCYYDYDDEEEEEEEDDSAGATGGEEVNEEDPKGIPDFWLTVLKNV 251

  Fly   158 AIMSEMVQPHDEPAIRKLIDISIKY-DNGH--SYTLEFHFDKNEYFSNSVLTKQYVLKSTVDPND 219
            ..::.|::.:|||.::.|.||.:|. |.|.  |:||||||..||||.|.:|||.|||||.:...|
Mouse   252 EALTPMIKKYDEPILKLLTDIKVKLSDPGEPLSFTLEFHFKPNEYFKNELLTKTYVLKSKLACYD 316

  Fly   220 PFAFEGPEIYKCTGCTINWEKKMNLTVKTIRKKQKHKERGAVRTIVKQVPTDSFFNFFSPPEVPS 284
            |..:.|..|...|||.|:|.:..|:|::||:|||:|:..|.|||:.:..|.|||||||||..:..
Mouse   317 PHPYRGTAIEYATGCDIDWNEGKNVTLRTIKKKQRHRVWGTVRTVTEDFPKDSFFNFFSPHGISL 381

  Fly   285 DQEEVDDDSQQILATDFEIGHFLRARIIPKAVLYYTGDIVDDEDDEDEEEYDENEEDE--YDD 345
            :..:.:|        ||.:||.||..|||::||:::||.::.:.:....|.::...|:  |||
Mouse   382 NGGDEND--------DFLLGHNLRTYIIPRSVLFFSGDALESQQEGVVREVNDEIYDKIIYDD 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nap1	NP_001246485.1	NAP	55..321	CDD:279323	114/307 (37%)
Nap1l2	NP_032697.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..87		4/22 (18%)
		NAP	111..410	CDD:279323	114/306 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..238		5/24 (21%)
		Nuclear localization signal. /evidence=ECO:0000255	346..352		4/5 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842124
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1507
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53841
OrthoDB	1	1.010	-	-		D1216172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11875
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X426
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.820