DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13562 and PNLIPRP3

DIOPT Version :9

Sequence 1:	NP_001246484.1	Gene:	CG13562 / 37797	FlyBaseID:	FBgn0034928	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001011709.2	Gene:	PNLIPRP3 / 119548	HGNCID:	23492	Length:	467	Species:	Homo sapiens

Alignment Length:	321	Identity:	66/321 - (20%)
Similarity:	104/321 - (32%)	Gaps:	104/321 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 NTKTMETSAYDDAYDLSGSGCSPTDKFA-IVLHGWIQSCSDEWALSLIERLSYYRGGCVICIDYS 132
            |:.|::.|.:.            |||.. |.:.||  ....:|...:...|........|.:|:
Human    74 NSSTIQASYFG------------TDKITRINIAGW--KTDGKWQRDMCNVLLQLEDINCINLDW- 123

  Fly   133 VVASSSYMRLYTNFDTLTGAISSIILTLFRQ-GFDPKRGYMFGFSFGGQLASAVGRSLRPHHIIE 196
            :..|..|:....|...:...::..|..|.:: .:.|.:.::.|.|.|..||...|..:..   :.
Human   124 INGSREYIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLAGEAGSRIPG---LG 185

  Fly   197 SIDTCDMAGPGF----DPIAVDHSKAGKHVQCFHSSRDK-------GTFVYSCHRNIMLGSCGLK 250
            .|...|.|||.|    ..:.:|.|.| ..|...|::..:       ||          :.:||
Human   186 RITGLDPAGPFFHNTPKEVRLDPSDA-NFVDVIHTNAARILFELGVGT----------IDACG-- 237

  Fly   251 QPSVASQLHL------GSH--GLCVDI---------------YINTFD------YPFYAVNYTPP 286
                    ||      |.|  | |.|:               ..:.||      |.|||.:...|
Human   238 --------HLDFYPNGGKHMPG-CEDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESILNP 293

  Fly   287 ECFTWQKTAKIPDGYTVGYE-ENFDSQVTGQIF------VPTSLHYPYNLSKKQLKLLTKG 340
            :.|             :.|. .::.|...|..|      .||..|:......|.:|  |.|
Human   294 DAF-------------IAYPCRSYTSFKAGNCFFCSKEGCPTMGHFADRFHFKNMK--TNG 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13562	NP_001246484.1	Abhydrolase	64..>208	CDD:304388	30/140 (21%)
PNLIPRP3	NP_001011709.2	Lipase	18..352	CDD:278576	66/321 (21%)
		Pancreat_lipase_like	52..348	CDD:238363	66/321 (21%)
		PLAT_PL	355..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010