Protein Alignment Lpt and BAZ1B

DIOPT Version :9

• Sequence 1: NP_611847.2
• Gene: Lpt / 37795
• FlyBaseID: FBgn0263667
• Length: 1482
• Species: Drosophila melanogaster
• Sequence 2: NP_001357331.1
• Gene: BAZ1B / 9031
• HGNCID: 961
• Length: 1483
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 85/421 - (20%)
• Similarity: 148/421 - (35%)
• Gaps: 149/421 - (35%)

  Fly   307 RTPGGGSSSRWHSHYTICDSCYQQRNKGFSCPICQKAYRAASHKEMVKCSWCNKFVHSTCDEEAD 371
            |||.|  :.|.|:.|.:    :.....|.                .::..|    ||.:.|...:
Human   900 RTPIG--TDRNHNRYWL----FSDEVPGL----------------FIEKGW----VHDSIDYRFN 938

  Fly   372 LTAYH-KKKEQNPDYDYVCPNCKSNSSGPGSSQQTIDSIVLSAMDSSSEQLSLKEIELD---PLE 432
               :| |....:.|.|| ||..|..:.|..:|..|             :..:..|:.::   |.:
Human   939 ---HHCKDHTVSGDEDY-CPRSKKANLGKNASMNT-------------QHGTATEVAVETTTPKQ 986

  Fly   433 GKPT--MDPSSDELHKLPTGKKKVCLTSVRGRSGKFVLHRMGVM-SQINKKRSTR---------- 484
            |:..  :..|..||.:|..     |            ||..|:. ||:.::...|
Human   987 GQNLWFLCDSQKELDELLN-----C------------LHPQGIRESQLKERLEKRYQDIIHSIHL 1034

  Fly   485 GKGRQLALPTISSDRCLSRSMETDL-----------------TSD--------KKL--------- 515
            .:...|.|.:...::.|...:.:||                 ||:        :||
Human  1035 ARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYVEETSEFEARVISLEKLKDFGECVIA 1099

  Fly   516 LLCSARDKF-------------IQAQDICVMCGSLGIESDSVMITCAQCGQCYHPYCAGVKPSR- 566
            |..|...||             :|::|   ...:..::.:..|:..|:.......:...::.::
Human  1100 LQASVIKKFLQGFMAPKQKRRKLQSED---SAKTEEVDEEKKMVEEAKVASALEKWKTAIREAQT 1161

  Fly   567 --------GILQKGWRCLDCTV------CEGCGKKNDEARLLLCDECDISYHIYCVNPPLETVPT 617
                    |:|.   .|:...:      |:.|.||.::.:|:|||||:.::|::|:.|.|..||.
Human  1162 FSRMHVLLGMLD---ACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPD 1223

  Fly   618 GNWKCSFCTLC----QKCGRNPTEKSEFGDS 644
            |.|:|..|...    ...|||.||:|...||
Human  1224 GEWQCPACQPATARRNSRGRNYTEESASEDS 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984
		PHD2_KMT2C_like	252..298	CDD:276985
		PHD_SF	337..392	CDD:304600	11/55 (20%)
		PHD4_KMT2C_like	530..578	CDD:276987	5/56 (9%)
		PHD5_KMT2C_like	580..625	CDD:276988	19/50 (38%)
		PHD6_KMT2C_like	657..707	CDD:276989
		NHP6B	1101..>1237	CDD:227935
		HMG	1173..1231	CDD:197700
BAZ1B	NP_001357331.1	WAC_Acf1_DNA_bd	21..120	CDD:337781
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..212
		C motif	207..213
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	302..333
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	379..432
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	446..470
		DDT	604..668	CDD:214726
		DUF5401	<664..>877	CDD:340095
		WHIM1	727..767	CDD:339506
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	788..817
		WSD	898..1025	CDD:317927	36/184 (20%)
		PHD_BAZ1B	1186..1231	CDD:277098	19/44 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1237..1326		8/18 (44%)
		Bromo_WSTF_like	1344..1440	CDD:99937
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1455..1483

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900