DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lpt and AT3G08020

DIOPT Version :9

Sequence 1:	NP_611847.2	Gene:	Lpt / 37795	FlyBaseID:	FBgn0263667	Length:	1482	Species:	Drosophila melanogaster
Sequence 2:	NP_187459.2	Gene:	AT3G08020 / 819993	AraportID:	AT3G08020	Length:	779	Species:	Arabidopsis thaliana

Alignment Length:	775	Identity:	168/775 - (21%)
Similarity:	257/775 - (33%)	Gaps:	247/775 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 SDNNVECLSCSSLGD------LSKLIMCSTCGDHFHSTCIGLANLPDTR-----SGWNCARCTKC 253
            |..|:.|..| .||:      ..:::.|..||..:|..|  |.:....|     |.|:|..|..|
plant   142 SGMNIMCRMC-FLGEGEGSDRARRMLSCKDCGKKYHKNC--LKSWAQHRDLFHWSSWSCPSCRVC 203

  Fly   254 QICRQQ-DSNDTKYVKCEQCQKTYHASCLRPVISAIPKYGWKCNRCRVCTDCGSRTPGGGSSSRW 317
            ::||:. |.|  |::.|::|...||..|..|....:....:.|.:...|..|.|..||.|.|.||
plant   204 EVCRRTGDPN--KFMFCKRCDAAYHCYCQHPPHKNVSSGPYLCPKHTRCHSCDSTVPGNGLSVRW 266

  Fly   318 HSHYTICDSCYQQRNKGFSCPICQKAYRAASHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQN 382
            ...||.||:|.:...||..||:|.|.||.:....||.|..|.::||..||..:|  ..:.:.:.:
plant   267 FLSYTCCDACGRLFVKGNYCPVCLKVYRDSESTPMVCCDICQRWVHCHCDGISD--DKYMQFQVD 329

  Fly   383 PDYDYVCPNCKSNSSGPGSSQQTIDSIVLSAMDSSSEQLSLKEI-------ELDPLEGKPTMD-- 438
            ....|.|..|:      |...|..|     ..|:..|....|::       .|....|.||.:
plant   330 GKLQYKCATCR------GECYQVKD-----LQDAVQELWKKKDVVDKELIASLRAAAGLPTEEEI 383

  Fly   439 ----PSSDELHKLPTGKKKVCLTSVRGRSGKFVLHRMGVMSQINKKRSTRGK---GRQLALPTIS 496
                |.||:....|          |.|||.||.:  .|::.:..||....||   .::.|....|
plant   384 FSIFPFSDDEENGP----------VSGRSLKFSI--KGLVEKSPKKSKEYGKHSSSKKHASKKGS 436

  Fly   497 SDRCLSRSMETDLTSDKKLL------------------------LCSARD-KFIQAQDICVMCGS 536
            ..: |...:..::.|:::.|                        :||..: |.::.:.:
plant   437 HTK-LEPEVHQEIGSERRRLGGVRIDNVGFQINEQSDVNSSVAGICSTHEPKIVKHKRV------ 494

  Fly   537 LGIESDSVMITCAQCGQCYHPYCAGVKPSRGILQKGWRCLDCTVCEGCGKKNDEARLLLCDECDI 601
                 |.||:|..:            ||||.:..|            |.|.:|.      |..|
plant   495 -----DDVMVTDEE------------KPSRIVRIK------------CSKPHDS------DSED- 523

  Fly   602 SYHIYCVNPPLETVPTGNWKCSFCTLCQKCGRNPTEKSEFGDSNMLECPSCTSQSSCPVCKVSYS 666
                                    ||     ||.      |:...::..............||.|
plant   524 ------------------------TL-----RNA------GEEKSVKAKKLVINLGARKINVSGS 553

  Fly   667 NGEMIIQCEHCELWAHFHCDSVNAQLTIDHYDNNVYKCFKCRCSTRSTNSL-ADAKFGNEDSLAI 730
            :...::        :|...|...:.|..|..|           .|....:| ...:||...|
plant   554 SKSNVV--------SHLSRDKDQSTLGGDKVD-----------QTGEVRTLKISGRFGKTQS--- 596

  Fly   731 TPQGSKPFVHITASSGPSFDSKSGAERNHPTLSGDMPESAPEALHWIDGVCLSESGLGMIKSLST 795
              :|||    .|..|...|.:.|.:|.||   ..|....:|                    :|..
plant   597 --EGSK----ATFGSVTQFPAASTSEGNH---VDDKTSISP--------------------ALQK 632

  Fly   796 EIKRKRKMRQALGNGKDGQLEAAAEEALEKYKDGMVWDGTENAIPEGFTISINDEGVNILRKKRQ 860
            |.:...|.:                  |.|...|   |.|.:.     |....||.::..:.:|.
plant   633 EARPLLKFK------------------LRKPNSG---DQTSSV-----TTQSEDEKLSSAKGQRS 671

  Fly   861 RNLQKLGIGGFSVRNRGLKKDSEETTAVDQINS----LMTMDKKKKIIRKKQKNKLIEAY 916
            :..:...:    |....||:|.|.||...|.||    :|..:...|.:.|....|.:|.:
plant   672 KRKRPSSL----VDMASLKEDGEATTHSHQDNSRNDEMMDANWILKKLGKDSIGKRVEVH 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984	14/55 (25%)
		PHD2_KMT2C_like	252..298	CDD:276985	13/46 (28%)
		PHD_SF	337..392	CDD:304600	17/54 (31%)
		PHD4_KMT2C_like	530..578	CDD:276987	9/47 (19%)
		PHD5_KMT2C_like	580..625	CDD:276988	5/44 (11%)
		PHD6_KMT2C_like	657..707	CDD:276989	8/49 (16%)
		NHP6B	1101..>1237	CDD:227935
		HMG	1173..1231	CDD:197700
AT3G08020	NP_187459.2	PHD_SF	203..245	CDD:304600	12/43 (28%)
AT3G08020	NP_187459.2	PHD_SF	285..339	CDD:304600	17/55 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3439
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900