Protein Alignment Lpt and Brd3

DIOPT Version :9

• Sequence 1: NP_611847.2
• Gene: Lpt / 37795
• FlyBaseID: FBgn0263667
• Length: 1482
• Species: Drosophila melanogaster
• Sequence 2: NP_001107046.1
• Gene: Brd3 / 67382
• MGIID: 1914632
• Length: 743
• Species: Mus musculus
• Alignment Length: 571
• Identity: 105/571 - (18%)
• Similarity: 192/571 - (33%)
• Gaps: 191/571 - (33%)

  Fly   873 VRNRGLKKDSEETT----AVDQINS----LMTMDKKKKIIRKKQKNKLIEAYPVYLQEAFFGKPL 929
            |:.:|:|:.::.||    |:....|    .::..|:.|::.:::..               |:|:
Mouse   236 VKKKGVKRKADTTTPTTSAITASRSESPPPLSEPKQAKVVARRESG---------------GRPI 285

  Fly   930 ------LEGGE--------------LVMADTDSSDEIDASMKVY---FTRP-EGKSPANQDTLAV 970
                  ||.||              |...|:...:.:......|   |.:| :.::....|...:
Mouse   286 KPPKKDLEDGEVPQHAGKKGKLSEHLRHCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDI 350

  Fly   971 NKSP--AKTVKKVKAELKTENKTVFIQQMPMGIQNKNGTTPVSNVFDPLQAEISNTVFANRH--- 1030
            .|.|  ..|||:.....:..:...|...:.:...|.....|..:....:..::.: ||..|.
Mouse   351 IKHPMDLSTVKRKMDSREYPDAQGFAADIRLMFSNCYKYNPPDHEVVAMARKLQD-VFEMRFAKM 414

  Fly  1031 PLDALASPNVPELDMANSVSTVPSAEVIEK---PMRESPAVLVDSFMVPNQLP--------QEQ- 1083
            |.:.:.:|.:|          .|:|.::.|   ..|.|.....||....::..        |||
Mouse   415 PDEPMEAPALP----------APTAPIVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQT 469

  Fly  1084 ---KFHNQLY-LGGNTLVNPAQQLQFRQQAPQNANKQNMQTIMSQVVLQTEKRPEEEQKVVEPVT 1144
               .|.:||. :....|....:||....|||.|..|:           :.||:.:|::|
Mouse   470 GCGAFQDQLLNVSSVQLKAVHEQLAALSQAPVNKPKK-----------KKEKKEKEKKK------ 517

  Fly  1145 ETLNAGTQKTAEKMRKDEDLGLMATISAVLYANTEHPNLKELFPIWNDRCKQILKRWRSLCNEKK 1209
            :..:...:|...|.:.:|:....|..:|                      ||        ..:||
Mouse   518 KDKDKDKEKEKHKAKSEEEKKAKAAPAA----------------------KQ--------AQQKK 552

  Fly  1210 APFLQKAKDNRSALRQ--------------RREQNKIPMPPKPQKQ----------EEMGRV--- 1247
            || .:||....:|.||              ..|:..:||....::|          |::|||
Mouse   553 AP-TKKANSTTTASRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHI 616

  Fly  1248 -WKQPPKLKEDQPNM----FVTYNGNAY-DMGNYVGGSAQAASNNPNPHHVMPNVNDNLVIKATM 1306
             ..:.|.|::..|:.    |.|...... ::..||....|.....|               .:|.
Mouse   617 IQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKP---------------LSTS 666

  Fly  1307 QRTQVHTTAASTLKMTTVDNRLELNTAVYGTEPIGDKKLRNLL-QKNSTEP 1356
            .:.|    ||.:.:....:.:.||           :|:|:::. |.||.:|
Mouse   667 GKKQ----AAKSKEELAQEKKKEL-----------EKRLQDVSGQLNSKKP 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984
		PHD2_KMT2C_like	252..298	CDD:276985
		PHD_SF	337..392	CDD:304600
		PHD4_KMT2C_like	530..578	CDD:276987
		PHD5_KMT2C_like	580..625	CDD:276988
		PHD6_KMT2C_like	657..707	CDD:276989
		NHP6B	1101..>1237	CDD:227935	30/149 (20%)
		HMG	1173..1231	CDD:197700	12/71 (17%)
Brd3	NP_001107046.1	Bromo_Brdt_I_like	33..139	CDD:99929
		Bromo_Brdt_II_like	310..411	CDD:99930	16/101 (16%)
		BET	589..653	CDD:374956	14/63 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900