DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lpt and CG31109

DIOPT Version :9

Sequence 1:	NP_611847.2	Gene:	Lpt / 37795	FlyBaseID:	FBgn0263667	Length:	1482	Species:	Drosophila melanogaster
Sequence 2:	NP_001262946.1	Gene:	CG31109 / 43001	FlyBaseID:	FBgn0051109	Length:	198	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	38/213 - (17%)
Similarity:	75/213 - (35%)	Gaps:	45/213 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   567 GILQKGWRCLDCTVCEGCGK---------KNDEARLLLCDECDISYHIYCVNPPLETVPTGNWKC 622
            |.::|.  |:...:|..|.:         .:...||.|.::  |:.::.....|.:.:|.
  Fly     2 GSIEKA--CISGFLCRLCSEMHRTVIHIYSDHGQRLCLVEK--INGYLPITISPTDPLPK----- 57

  Fly   623 SFCTLCQKCGRNPTEKSEFGDSNMLECPSCTSQSSCPVCKVSYSNGEMIIQCEHCELWAHFHCDS 687
               |:|:.|    ..:.|...|.::.......:....:.|........|...|..|       |.
  Fly    58 ---TICKSC----LHRVEQHYSLLMRLTRMREERKFKLIKYKAQRNPSISSVESEE-------DV 108

  Fly   688 VNAQLTIDHYDNNVYKCFKCRCSTRSTNSLADAKFGNEDSLAITPQGSKPFV--------HITAS 744
            :|:....:..:.|.    :.:.:.||.::...|:.|.:...:.:|:.:|..|        |..:.
  Fly   109 INSSSVHEFPNRNE----EDQATRRSESTSTQAETGPQTQESQSPKSTKTAVSTPNSSESHDASG 169

  Fly   745 SGPS-FDSKSGAERNHPT 761
            :||| .|.|.....|..|
  Fly   170 AGPSNRDRKETGTGNSET 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984
		PHD2_KMT2C_like	252..298	CDD:276985
		PHD_SF	337..392	CDD:304600
		PHD4_KMT2C_like	530..578	CDD:276987	3/10 (30%)
		PHD5_KMT2C_like	580..625	CDD:276988	8/53 (15%)
		PHD6_KMT2C_like	657..707	CDD:276989	7/49 (14%)
		NHP6B	1101..>1237	CDD:227935
		HMG	1173..1231	CDD:197700
CG31109	NP_001262946.1	zf-AD	13..76	CDD:214871	13/76 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900