DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lpt and Baz1b

DIOPT Version :9

Sequence 1:NP_611847.2 Gene:Lpt / 37795 FlyBaseID:FBgn0263667 Length:1482 Species:Drosophila melanogaster
Sequence 2:NP_001178845.1 Gene:Baz1b / 368002 RGDID:1597089 Length:1476 Species:Rattus norvegicus


Alignment Length:418 Identity:88/418 - (21%)
Similarity:149/418 - (35%) Gaps:144/418 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   307 RTPGGGSSSRWHSHYTICDSCYQQRNKGFSCPICQKAYRAASHKEMVKCSWCNKFVHSTCDEEAD 371
            |||.|  :.|.|:.|.:    :.....|.                .::..|    ||::.|..  
  Rat   898 RTPIG--TDRNHNRYWL----FSNEVPGL----------------FIEKGW----VHNSIDYR-- 934

  Fly   372 LTAYHKKKEQN-PDYDYVCPNCKSNSSGPGSSQQTIDSIVLSAMDSSSEQLSLKEIELDPLEGKP 435
             ..:|:|...| ||.|| ||..|..:.|..:|........|.|::::.           |.:|:.
  Rat   935 -FKHHRKDHNNLPDDDY-CPRSKKANLGKNASVNAHLGSALEAVETTV-----------PKQGQN 986

  Fly   436 T--MDPSSDELHKLPTGKKKVCLTSVRGRSGKFVLHRMGVM-SQINKKRSTR----------GKG 487
            .  :..|..||.:|..     |            ||..|:. ||:.::...|          .:.
  Rat   987 LWFLCDSQKELDELLN-----C------------LHPQGIRESQLKERLEKRYQEITHSIHLARK 1034

  Fly   488 RQLALPTISSDRCLSRSMETDL-----------------TSD--------KKL---------LLC 518
            ..|.|.:...::.|...:.:||                 ||:        :||         |..
  Rat  1035 PNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTSEFEARVISLEKLKDFGECVIALQA 1099

  Fly   519 SARDKF-------------IQAQDICVMCGSLGIESDSVMITCAQCGQCYHPYCAGVKPSR---- 566
            |...||             :|::|   ...|..::.:..|:..|:.......:...::.::    
  Rat  1100 SVIKKFLQGFMAPKQKKRKLQSED---STKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSR 1161

  Fly   567 -----GILQKGWRCLDCTV------CEGCGKKNDEARLLLCDECDISYHIYCVNPPLETVPTGNW 620
                 |:|.   .|:...:      |:.|.||.::.:|:|||||:.::|::|:.|.|..||.|.|
  Rat  1162 MHVLLGMLD---ACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEW 1223

  Fly   621 KCSFC----TLCQKCGRNPTEKSEFGDS 644
            :|..|    ......|||.||:|...||
  Rat  1224 QCPACQPPTARRNSRGRNYTEESTSEDS 1251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LptNP_611847.2 ePHD1_KMT2C_like 109..191 CDD:277135
PHD1_KMT2C_like 205..250 CDD:276984
PHD2_KMT2C_like 252..298 CDD:276985
PHD_SF 337..392 CDD:304600 13/55 (24%)
PHD4_KMT2C_like 530..578 CDD:276987 6/56 (11%)
PHD5_KMT2C_like 580..625 CDD:276988 19/50 (38%)
PHD6_KMT2C_like 657..707 CDD:276989
NHP6B 1101..>1237 CDD:227935
HMG 1173..1231 CDD:197700
Baz1bNP_001178845.1 WAC_Acf1_DNA_bd 21..120 CDD:287503
DDT 602..666 CDD:214726
WHIM1 722..771 CDD:292246
WHIM2 897..925 CDD:292247 8/48 (17%)
WHIM3 988..1026 CDD:292248 11/54 (20%)
PHD_BAZ1B 1183..1228 CDD:277098 19/44 (43%)
Bromo_WSTF_like 1337..1433 CDD:99937
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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