DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lpt and Tbrg1

DIOPT Version :9

Sequence 1:	NP_611847.2	Gene:	Lpt / 37795	FlyBaseID:	FBgn0263667	Length:	1482	Species:	Drosophila melanogaster
Sequence 2:	NP_001009344.2	Gene:	Tbrg1 / 300521	RGDID:	1305123	Length:	406	Species:	Rattus norvegicus

Alignment Length:	238	Identity:	52/238 - (21%)
Similarity:	77/238 - (32%)	Gaps:	69/238 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   642 GDSNMLECPSCTSQSSCPVCKVS------YSNGEMIIQCEHCELWAHFHCDSVNAQLTIDHYDNN 700
            |.:..|..|.....|..||..:.      ||.||:|..      ...||.:  ||...:.:....
  Rat   159 GGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITN------RPGFHDE--NAIYPVGYCSTR 215

  Fly   701 VYKCFKC---RC---------------------STRST--NSLADAKFGNEDSLAITPQGSKPFV 739
            ||...||   :|                     ..|:|  .|.|||.:  |:.|......:...:
  Rat   216 VYASMKCPDQKCLYTCQIKDGGVQPQFEIVPEDDPRNTIVGSSADACY--EELLRAISAATGKLM 278

  Fly   740 HITASSGPSFDSKSGAERNHPTLSGDMPESAPEA-----LHWID-GVCLSESGLGMIKSLSTEIK 798
            ....|.|..|...|     |||:. ::.:|.|||     ..|:. ..|....|     .||.|:.
  Rat   279 PNPLSCGADFFGFS-----HPTIH-NLIQSCPEAQNCVNYQWVKFDACKPRKG-----QLSQELP 332

  Fly   799 RKRKMRQALGNGKDGQLEAAAEEALEKYKDGMVWDGTENAIPE 841
            .         |.....|||...:..:...:..:..|:.: :||
  Rat   333 E---------NDAAMSLEAFPTQTFDDDHEDSILPGSLD-LPE 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984
		PHD2_KMT2C_like	252..298	CDD:276985
		PHD_SF	337..392	CDD:304600
		PHD4_KMT2C_like	530..578	CDD:276987
		PHD5_KMT2C_like	580..625	CDD:276988
		PHD6_KMT2C_like	657..707	CDD:276989	13/55 (24%)
		NHP6B	1101..>1237	CDD:227935
		HMG	1173..1231	CDD:197700
Tbrg1	NP_001009344.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..144
		FYRN	183..233	CDD:399155	14/57 (25%)
		FYRC	239..320	CDD:399156	20/88 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900