DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lpt and Tbrg1

DIOPT Version :9

Sequence 1:	NP_611847.2	Gene:	Lpt / 37795	FlyBaseID:	FBgn0263667	Length:	1482	Species:	Drosophila melanogaster
Sequence 2:	NP_079565.2	Gene:	Tbrg1 / 21376	MGIID:	1100877	Length:	406	Species:	Mus musculus

Alignment Length:	240	Identity:	50/240 - (20%)
Similarity:	80/240 - (33%)	Gaps:	63/240 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   637 EKSEFGDSNMLECPSCTSQSSCPVCKVS------YSNGEMIIQCEHCELWAHFHCDSVNAQLTID 695
            :|...|.:..|..|.....|..||..:.      ||.||:|..      ...||.:  ||...:.
Mouse   154 KKKMEGGARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITN------RPGFHDE--NAIYPVG 210

  Fly   696 HYDNNVYKCFKC---RCSTRSTNSLADAKFGNEDSLAITPQGSKPFVHITASSGPSFDS------ 751
            :....||...||   :|  ..|..:.|.  |.:....|.|:.......:.:|:...::.
Mouse   211 YCSTRVYASMKCPDQKC--LYTCQIKDG--GVQPQFEIVPEDDPQNTIVGSSADACYEELLRAIS 271

  Fly   752 -----------KSGAE---RNHPTLSGDMPESAPEA-----LHWID-GVCLSESGLGMIKSLSTE 796
                       ..||:   .:|||:. ::.:|.|||     ..|:. ..|....|     .||.|
Mouse   272 ATTGKLMPNPLSCGADFFGFSHPTIH-NLIQSCPEAQNCVNYQWVKFDACKPRKG-----QLSQE 330

  Fly   797 IKRKRKMRQALGNGKDGQLEAAAEEALEKYKDGMVWDGTENAIPE 841
            :..         |.....|||...:..:...|..:..|:.: :||
Mouse   331 LPE---------NDATMSLEAFQTQTFDDDHDDSILPGSLD-LPE 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984
		PHD2_KMT2C_like	252..298	CDD:276985
		PHD_SF	337..392	CDD:304600
		PHD4_KMT2C_like	530..578	CDD:276987
		PHD5_KMT2C_like	580..625	CDD:276988
		PHD6_KMT2C_like	657..707	CDD:276989	13/55 (24%)
		NHP6B	1101..>1237	CDD:227935
		HMG	1173..1231	CDD:197700
Tbrg1	NP_079565.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	109..144
		FYRN	184..233	CDD:283589	15/58 (26%)
		FYRC	239..314	CDD:283590	12/75 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900