DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lpt and C29F9.5

DIOPT Version :9

Sequence 1:	NP_611847.2	Gene:	Lpt / 37795	FlyBaseID:	FBgn0263667	Length:	1482	Species:	Drosophila melanogaster
Sequence 2:	NP_001355379.1	Gene:	C29F9.5 / 183022	WormBaseID:	WBGene00016220	Length:	261	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	45/230 - (19%)
Similarity:	85/230 - (36%)	Gaps:	53/230 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1107 QQAPQNANKQNMQTIMSQ---VVLQTEKRPEEEQKVVEPVTETLNAGTQKTAEKMRKDEDLGLMA 1168
            ||.|: .:...|.|::|:   ::|...:....:.|:.|...:     .:.....|.|.:|..:|.
Worm    26 QQQPR-VSTATMNTLISRQLGLLLHAHECVRRDIKIREAAEK-----NEPAPHAMCKIQDCVIMK 84

  Fly  1169 TISAVLYANTEHPNLKELFPIWNDRC---KQILKRWRSLCNEKKAPFLQKAKDNRSALRQRREQN 1230
            .:...:.:..|.|....:      .|   :.||..|:...|| :.|..:...:.|:|    ..|:
Worm    85 EVLKHMTSCKEGPKCNSV------HCASSRTILSHWKKCFNE-ECPVCKPIIEQRTA----PPQD 138

  Fly  1231 KIPMPPKPQKQEEMGRVWK-QPPKLKEDQPNMFVTYNGNAYDMGNYVGGSAQAASNNPNPHHVMP 1294
            ..|..|   |:.|..::|. :.||          ||.....:. .|.|              :|.
Worm   139 TTPAEP---KKPEHDQIWHLEVPK----------TYRSELIEK-IYKG--------------IMS 175

  Fly  1295 NVNDNLVIKATMQRTQVHTTAASTLKMTTVDNRLE 1329
            ||....:.:|.|...:.::.:|. |::.....:||
Worm   176 NVKPGTLSEAQMDTWKEYSRSAE-LQIFDTAQKLE 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lpt	NP_611847.2	ePHD1_KMT2C_like	109..191	CDD:277135
		PHD1_KMT2C_like	205..250	CDD:276984
		PHD2_KMT2C_like	252..298	CDD:276985
		PHD_SF	337..392	CDD:304600
		PHD4_KMT2C_like	530..578	CDD:276987
		PHD5_KMT2C_like	580..625	CDD:276988
		PHD6_KMT2C_like	657..707	CDD:276989
		NHP6B	1101..>1237	CDD:227935	26/135 (19%)
		HMG	1173..1231	CDD:197700	12/60 (20%)
C29F9.5	NP_001355379.1	ZnF_TAZ	40..128	CDD:214717	17/99 (17%)
C29F9.5	NP_001355379.1	KIX	153..223	CDD:280354	16/83 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900