DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lpt and athp-2

DIOPT Version :9

Sequence 1:NP_611847.2 Gene:Lpt / 37795 FlyBaseID:FBgn0263667 Length:1482 Species:Drosophila melanogaster
Sequence 2:NP_494767.2 Gene:athp-2 / 173769 WormBaseID:WBGene00019217 Length:1412 Species:Caenorhabditis elegans


Alignment Length:471 Identity:79/471 - (16%)
Similarity:144/471 - (30%) Gaps:186/471 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   377 KKKEQNPDYDYVCPNCKSNSSGPGSSQQTIDSIVLSAMDSSSEQLSLKEI----ELDPLEGKPTM 437
            |::::.|....:..:.|:.:.|....::.:|:|||.::..:|  |||.||    ||...|.|..|
 Worm   719 KEQKEPPVVRRLKAHIKAINEGRRYDKEDLDAIVLESVPYAS--LSLDEIVTARELQKSEFKILM 781

  Fly   438 DPSSDELHKLPTGKKKVCLTSVRGRSGKFVLHRMGVM---------------------------- 474
            |....::.::.:....:.|.|.|......|:..:..:                            
 Worm   782 DSLISKMFQIYSKISDIRLGSDRAYRRYIVMENLSAILVETATFQELGIYCDEPSIIDDPLNLLE 846

  Fly   475 --------------------------------------SQINKKRSTRGKGRQLAL--------P 493
                                                  .|:.|..:.|| .|::.|        |
 Worm   847 NEHQEVFICTGNMDTCRVHGDESNNWTRWSYIRDREQFEQLLKSLNPRG-NREVELLEELNEYRP 910

  Fly   494 TI---------------SSDRCLSRSMETD------------------------------LTSDK 513
            ::               ..|...|:.|..|                              :.|.:
 Worm   911 SLLEILEETERLHEEEEDEDEWKSQFMTNDPNPGDTYNIDWDAEMRDLLLDFEEKIDQGQMGSIE 975

  Fly   514 KLLLCSA---RDKFIQAQDICVMCG---------SLGIE-----SDSVMITCA--QCGQCYH--- 556
            |:..|:.   ||...::.::|::..         |:.:|     |||:.:..|  ...:..|   
 Worm   976 KIFECNRIEWRDNLKESGNVCMLLNEDISIFGEISVNLEESEHFSDSMKLAIAFYMIIKSIHLKF 1040

  Fly   557 ---PYCAGVKPSRGILQKG-----WR--CLDCT-------------------------VCEGCGK 586
               ||.:..|...|.|:..     |:  .|:|.                         .|..|.:
 Worm  1041 IKAPYISPNKDEHGNLKPSELFIRWQRALLECESHSALSLFISTFEGSIKWDKSRLQGKCRSCRR 1105

  Fly   587 KNDEARLLLCDECDISYHIYCVNPPLETVPTGNWKCSFCTLCQKCGRNPTEKSEFGDSNMLECPS 651
            |.....|:||.|||..||:.|....:.:....:|.|:.|...|:...|..::....|..:.|   
 Worm  1106 KAAAHDLVLCSECDNCYHLKCAKLDVNSDAPADWMCTSCRAQQRKVENEAKRMARDDDQLAE--- 1167

  Fly   652 CTSQSSCPVCKVSYSN 667
            .:||....:..:|.|:
 Worm  1168 SSSQEDVAIGNISISD 1183

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LptNP_611847.2 ePHD1_KMT2C_like 109..191 CDD:277135
PHD1_KMT2C_like 205..250 CDD:276984
PHD2_KMT2C_like 252..298 CDD:276985
PHD_SF 337..392 CDD:304600 2/14 (14%)
PHD4_KMT2C_like 530..578 CDD:276987 15/76 (20%)
PHD5_KMT2C_like 580..625 CDD:276988 14/44 (32%)
PHD6_KMT2C_like 657..707 CDD:276989 2/11 (18%)
NHP6B 1101..>1237 CDD:227935
HMG 1173..1231 CDD:197700
athp-2NP_494767.2 WAC_Acf1_DNA_bd 23..123 CDD:402251
DDT 457..524 CDD:214726
WHIM1 629..671 CDD:406127
WSD 795..897 CDD:406128 8/102 (8%)
PHD 1100..1144 CDD:214584 14/43 (33%)
BROMO 1306..1409 CDD:197636
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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