DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lpt and BAZ2A

DIOPT Version :9

Sequence 1:NP_611847.2 Gene:Lpt / 37795 FlyBaseID:FBgn0263667 Length:1482 Species:Drosophila melanogaster
Sequence 2:XP_011536103.1 Gene:BAZ2A / 11176 HGNCID:962 Length:1912 Species:Homo sapiens


Alignment Length:321 Identity:70/321 - (21%)
Similarity:112/321 - (34%) Gaps:123/321 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   333 KGFSCPICQKAYRAASHKEMVKCSWCNKFVHSTCDEEADLTAYHKKKEQNPDYDYVCPNCKSNSS 397
            :|::||...     ::.:::..|...:       |.:.|:|...:.:|.      :.|..|:.: 
Human  1536 RGWTCPSPD-----STREDLAYCEHLS-------DSQEDITWRGRGREG------LAPQRKTTN- 1581

  Fly   398 GPGSSQQTIDSIV--LSAMDSSSEQLSLKEIELDPLEGKPTMDPSSDE-LHKLPTGKKKVCLTSV 459
                   .:|..|  |:|::.:.|:..|:|    ||  .||.:...:: |...|.|..:...|.:
Human  1582 -------PLDLAVMRLAALEQNVERRYLRE----PL--WPTHEVVLEKALLSTPNGAPEGTTTEI 1633

  Fly   460 RGRSGKFVLHRMGVMSQINKKRSTRGKGRQLALPTI-----SSDRCLSRSMETDLTSDKKLLLCS 519
                           |.::..||..      ..|.|     :.:||.|                 
Human  1634 ---------------SPLSPSRSYE------ITPRIRVWRQTLERCRS----------------- 1660

  Fly   520 ARDKFIQAQDICVMCG----SLGIESDSVMITCAQCGQCYHPYCAGVKPSRGILQKGWRCLDCTV 580
                   |..:|:..|    |:..|.....:||..|                  :||        
Human  1661 -------AAQVCLCLGQLERSIAWEKSVNKVTCLVC------------------RKG-------- 1692

  Fly   581 CEGCGKKNDEARLLLCDECDISYHIYCVNPPLETVPTGNWKCSFCTLCQKCGRNPTEKSEF 641
                  .|||. |||||.||...||||..|.:|.||.|:|.|:.| |.|:.....|:|..|
Human  1693 ------DNDEF-LLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVC-LAQQVEGEFTQKPGF 1745

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LptNP_611847.2 ePHD1_KMT2C_like 109..191 CDD:277135
PHD1_KMT2C_like 205..250 CDD:276984
PHD2_KMT2C_like 252..298 CDD:276985
PHD_SF 337..392 CDD:304600 8/54 (15%)
PHD4_KMT2C_like 530..578 CDD:276987 9/51 (18%)
PHD5_KMT2C_like 580..625 CDD:276988 21/44 (48%)
PHD6_KMT2C_like 657..707 CDD:276989
NHP6B 1101..>1237 CDD:227935
HMG 1173..1231 CDD:197700
BAZ2AXP_011536103.1 HAT_MBD 551..623 CDD:238691
DDT 848..913 CDD:214726
WHIM3 1439..1477 CDD:292248
PHD_BAZ2A 1685..1731 CDD:277099 27/79 (34%)
Bromo_BAZ2A_B_like 1805..1901 CDD:99935
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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