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Protein Alignment Lpt and Nsd2

DIOPT Version :9

Sequence 1:	NP_611847.2	Gene:	Lpt / 37795	FlyBaseID:	FBgn0263667	Length:	1482	Species:	Drosophila melanogaster
Sequence 2:	NP_001074571.2	Gene:	Nsd2 / 107823	MGIID:	1276574	Length:	1366	Species:	Mus musculus

Alignment Length:	782	Identity:	165/782 - (21%)
Similarity:	240/782 - (30%)	Gaps:	295/782 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 EQKCNFCGRYGASINCKMNCRQVHHWPCAAAA----GCLLILESFTVFCTEHLSQVP--VICSDN 202
            |..|..|.:.|:.:.|:..|....|..|...:    |      .||  |||..|.:.  .:|.::
Mouse   668 EYVCQLCEKTGSLLLCEGPCCGAFHLACLGLSRRPEG------RFT--CTECASGIHSCFVCKES 724

  Fly   203 NVECLSCSSLGDLSKLIMCSTCGDHFHSTCIGLANLPDTRS-GWNCA--RCTKCQICRQQDSNDT 264
            .:|...|          :.:.||..:|..|:....|....| |:.|.  .|..|......:...:
Mouse   725 KMEVKRC----------VVNQCGKFYHEACVKKYPLTVFESRGFRCPLHSCMSCHASNPSNPRPS 779

  Fly   265 --KYVKCEQCQKTYHA--SCLRPVISAIPKYGWKCNRCRVCTDCGSRTPGGGSSSRWHSHYTI-- 323
              |.::|.:|...||.  :||....|.|      .:...:||  |..|...|  .|.|:|..:
Mouse   780 KGKMMRCVRCPVAYHGGDACLAAGCSVI------ASNSIICT--GHFTARKG--KRHHTHVNVSW 834

  Fly   324 CDSCYQQRNKGFSCPICQKAYRAASHK-----EMVKCSW-CN-----KFVH-------------- 363
            |..|    :||.|. :|.:|..||.|.     ||...|| ||     |.:|
Mouse   835 CFVC----SKGGSL-LCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRW 894

  Fly   364 ---STCDEEADLTAYHKKKEQNPDY--------DY-------VCPNCKSNSSGPGSSQQTIDSI- 409
               ..|..:.......|.|.:..::        ||       |.|..:.:.   ||..|.:..|
Mouse   895 WPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDR---GSRYQGVRGIG 956

  Fly   410 -----VLSAMDSSSEQLSL-----------------KEIELDPLEGKP---TMDPSSDELHKL-- 447
                 .|...::...::.|                 |.|:::...||.   |.|.|  |:.|.
Mouse   957 RVFKNALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADIS--EIPKCNC 1019

  Fly   448 ------PTGKKKVCLTSVRGRSGKFVLHRM------GVMSQINKKR--------STRGKGRQLAL 492
                  |.|....||    .|...|..|..      ...:|...||        .|.|||..|..
Mouse  1020 KPTDENPCGSDSECL----NRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVA 1080

  Fly   493 ---------------PTISSDRCLSR---SMETDLTSDKKLLLCSARDKFIQAQDICVMCGSLGI 539
                           ..|..:.|::|   :.|.|:|  ...:|...:|:.|.|       |..|.
Mouse  1081 KRDIRKGEFVNEYVGELIDEEECMARIKYAHENDIT--HFYMLTIDKDRIIDA-------GPKGN 1136

  Fly   540 ESDSVMITCAQCGQCYHPYCAGVK-----------------PSRGILQKGWRCLDC-----TVCE 582
            .|..:..:|       .|.|..:|                 |:...|...:. |||     |||.
Mouse  1137 YSRFMNHSC-------QPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYN-LDCLGNEKTVCR 1193

  Fly   583 GCGKKN-------------------------------------------------DEARLLLCDE 598
             ||..|                                                 |..:|:|||.
Mouse  1194 -CGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRRAKGEGKRQSEDECFRCGDGGQLVLCDR 1257

  Fly   599 --CDISYHIYCVNPPLETVPTGNWKCSFCTLCQKCGRNPTEKSEFGDSNMLECPSCTSQSSCP-- 659
              |..:||:.|:.  |...|.|.|:|.: ..|..||:                ||.:....||
Mouse  1258 KFCTKAYHLSCLG--LGKRPFGKWECPW-HHCDVCGK----------------PSTSFCHLCPNS 1303

  Fly   660 VCKV--------SYSNGEMIIQCEHCELWAHFHCDSVNAQLTIDHYDNNVY---KCFKCRCSTRS 713
            .||.        |..:|:... |||     ....||.::..|...:..::.   |..|.||..|.
Mouse  1304 FCKEHQDGTAFRSTQDGQSYC-CEH-----DLRADSSSSTKTEKPFPESLKSKGKRKKRRCWRRV 1362

  Fly   714 TN 715
            |:
Mouse  1363 TD 1364

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.