Protein Alignment Upf3 and upf3b

DIOPT Version :10

• Sequence 1: NP_611844.3
• Gene: Upf3 / 37792
• FlyBaseID: FBgn0034923
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_957248.1
• Gene: upf3b / 393929
• ZFINID: ZDB-GENE-040426-1630
• Length: 467
• Species: Danio rerio
• Alignment Length: 521
• Identity: 154/521 - (29%)
• Similarity: 248/521 - (47%)
• Gaps: 105/521 - (20%)

  Fly     1 MAETFAEEKPKEK-------SKASRRKDKKDKTNQIVKIVMRHLPPTMTEAQFLDQVGPLPENDS 58
            |.|.....:|:||       ....:.|..|:|...:.|||:|.||||:|:....:|:.||||.|.
Zfish     1 MKEDKENTRPREKKVEIKCDENDKQEKPCKEKKEAMTKIVIRRLPPTLTKEDLEEQLQPLPELDY 65

  Fly    59 YYYCKADWSLGQEATCRAYIDMSSKDIGEVVQFRDRFDGYVFVDHKGVEYMAIVEYAPFQCFLKN 123
            ..:..:|.||......|||::..::|  ::|.||||||||||:|::|.||.||||:||||...|.
Zfish    66 LEFFSSDTSLFPHLFARAYLNFKNQD--DIVLFRDRFDGYVFIDNRGQEYPAIVEFAPFQKVAKK 128

  Fly   124 KARNDDSKVNTIESEPHYQEFIKRLAQEREEASRMGDVKIDFNFERRTEE--KVKSTPLLQYLAN 186
            :::..|:|..||:.:..|::|::....:.|::....::.:: ..|.:|:|  ..|:||||.:|.|
Zfish   129 RSKKKDAKSGTIDDDADYKKFLEFYNGDEEKSPSNPEILLE-EIEAKTKELSSKKTTPLLDFLKN 192

  Fly   187 K---KEKRREEARRRNEEKRKQREEQKLLRLAAQSDASKLKEAEGGGGGGDTKKPAKKDVKDPQS 248
            |   :|:::||.|||..|:::.|||::  |...:.|..|.||||      ..||..|...||
Zfish   193 KQRIREEKKEERRRREIERKRLREEER--RKWREEDRRKRKEAE------KLKKVEKASEKD--- 246

  Fly   249 SGSQANDAKASRSKRRTERDQRRREEHEQRKLVKRDKKKDDGQGK--QDKQDKQDK-----GKPS 306
                              :|| .::|..:.||:::.:|.|||:.:  :||..|||:     .:||
Zfish   247 ------------------KDQ-HKDEQPKIKLLRKPEKADDGEAEKPKDKPKKQDRERQKEDRPS 292

  Fly   307 SG--KQNKNSKSMDIVILKKANKPESNESLDVPSTSNAAEASKEKPATENTETPEAAVKVFTPAA 369
            .|  |:.:|.:..:    :|..|||.....:........|..:::......:..|        ..
Zfish   293 GGDLKKRQNGEHRE----EKGGKPEDVGHKEYRDRDGERERDRDRERERRQKEKE--------RI 345

  Fly   370 RGGRKEKRTGADKQPAGSAHETAEEAIKAAQFRASEER--------------------------- 407
            |...:|:|...:.|...:.:...||..|..:.|..|:|
Zfish   346 RRQDEERRRRREHQDGENTYRKREEEGKKDKERVWEKRKNEHTGESSGSARPEKSSRDSKKEESA 410

  Fly   408 ---RIRNKDRPSIAIYQPKARIRASDELPQGAGGKDGSDGEASVVEEKTSKRNKRPNRRNKPKPK 469
               |:||||||:|.:|||.:|.|.     :|.||..|:.|:....|    ||.:|..::|:.|..
Zfish   411 RKDRLRNKDRPAIQLYQPGSRNRT-----RGGGGGGGTGGDGPAAE----KRAEREAKKNQEKGA 466

  Fly   470 E 470
            |
Zfish   467 E 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf3	NP_611844.3	Smg4_UPF3	27..186	CDD:460932	62/160 (39%)
upf3b	NP_957248.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		6/28 (21%)
		RRM_like_Smg4_UPF3B	36..123	CDD:410127	43/88 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..467		81/320 (25%)