Protein Alignment DNAlig1 and Lig3

DIOPT Version :10

• Sequence 1: NP_611843.2
• Gene: DNAlig1 / 37791
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_006532411.1
• Gene: Lig3 / 16882
• MGIID: 109152
• Length: 1065
• Species: Mus musculus
• Alignment Length: 821
• Identity: 200/821 - (24%)
• Similarity: 338/821 - (41%)
• Gaps: 198/821 - (24%)

  Fly     5 ITSFFKKKSDATDSPSPPKKVPKIDAKTELPD------EPHI----KSESASPETKPKVEPMSVD 59
            |...|:|...|..:....:.:.:::...||.|      ..||    ...:|:|:.|..|:.....
Mouse   195 IKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQISQHIADLSSKAAATPKKKAAVQAKLTT 259

  Fly    60 SEEKTSPVKNVKKEPKEVDDKTTDKKVTTIGL---NSTAATKEDVENYDPSADSYHPLKNAYWKD 121
            :.:.|||||..     .....|..:|.:....   ||..|..........||....|      |.
Mouse   260 TGQVTSPVKGA-----SFITSTNPRKFSGFSAKPNNSEQAPSSPAPGTSLSASKCDP------KH 313

  Fly   122 KKVTPYLALARTFQVIEETKGRLKMIDTLSNFFCSVMLVSP---------EDLVP---------- 167
            |.     .|.|.|:.:                 |:::..:|         .|.:.
Mouse   314 KD-----CLLREFRKL-----------------CAMVAENPSYNTKTQIIHDFLQKGSTGDGFHG 356

  Fly   168 SVYLSINQLAPAYEGLELGVAETTLMKAICKATGRNLAHIKSQ------TQLTGDL--GIVAEQS 224
            .|||::..|.|.            ::|::.....:.:..:.|:      ..:..||  |.|:|..
Mouse   357 DVYLTVKLLLPG------------VIKSVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETI 409

  Fly   225 RV--SQRMMFQPAP---LNVRDVFRKLREIAKLSGQ-SKMDLVYNMFVACRSSEARFFIRSLIGK 283
            |:  .|...|.||.   |.:::|...|..::||:.: .:...:.::...|.:::.:..||.:...
Mouse   410 RIFFEQSKSFPPAAKSLLTIQEVDAFLLHLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHD 474

  Fly   284 LRIGIAEQSLLTALAIGLVKKNHIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDIIIPAIL 348
            |::....:.:|.||.                 |:.|:            |:....|...::..:|
Mouse   475 LKMNSGAKHVLDALD-----------------PNAYE------------AFKASRNLQDVVERVL 510

  Fly   349 KYDIKELQERCPMHPG------------MPLRPMLAQPTKGVHEVFERF-GGMQITCEWKYDGER 400
             ::.:|:::    .||            .|::||||:..|.:....::. .||  ..|.||||||
Mouse   511 -HNEQEVEK----DPGRRRALRVQASLMTPVQPMLAEACKSIEYAMKKCPNGM--FSEIKYDGER 568

  Fly   401 AQIHRNEKGE-ISIFSRNSE----NNTAKYPDLIARSTALLKGDVKSYIIDSEIVAWDVERKQIL 460
            .|:|:  ||: .|.|||:.:    :..|.:.|.|.::   ..|. :|.|:|||::..|....:.|
Mouse   569 VQVHK--KGDHFSYFSRSLKPVLPHKVAHFKDYIPKA---FPGG-QSMILDSEVLLIDNNTGKPL 627

  Fly   461 PFQVLSTRKRKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATA 525
            ||..|...|:....    ...||:::||.:|.|..:|:.:.|.||||.|.::..|:.....|:..
Mouse   628 PFGTLGVHKKAAFQ----DANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIRNRIMFSEM 688

  Fly   526 LDTNDIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKRSRNWLKLKKDYLSN--VGDSLDLVV 588
            .......::...:...|:...|||::|  |.:.|||..|  |:|||:|||||:.  :.|:.||||
Mouse   689 KQVTKASDLADMINRVIREGLEGLVLK--DVKGTYEPGK--RHWLKVKKDYLNEGAMADTADLVV 749

  Fly   589 IGGYKGKGRRTGTYGGFLLACYDTENEEYQSICKIGTGFTDEDLQTHSEFLGKHVTSAAKSYYRY 653
            :|.:.|:|.:.|....||:.|||.:::::.::.|...|..|..|..    |.|.:.....|   .
Mouse   750 LGAFYGQGSKGGMMSIFLMGCYDPDSQKWCTVTKCAGGHDDATLAR----LQKELVMVKIS---K 807

  Fly   654 DPSLEPDHWF---------------EPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFI 703
            |||..|. |.               :...|||:..|:.|.|..|.|        .|||:||||..
Mouse   808 DPSKIPS-WLKINKIYYPDFIVPDPKKAAVWEITGAEFSRSEAHTA--------DGISIRFPRCT 863

  Fly   704 RIRDDKNSENATDANQVAHMYQ-SQDQ-----VKNNQKSST 738
            ||||||:.::||:..|:..:|| |:|:     |..::.|.|
Mouse   864 RIRDDKDWKSATNLPQLKELYQLSKDKADFAVVAGDEASPT 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	200/821 (24%)
Lig3	XP_006532411.1	zf-PARP	151..236	CDD:459887	7/40 (18%)
		dnl1	373..885	CDD:273147	153/577 (27%)
		LIG3_BRCT	989..1059	CDD:465260