Protein Alignment DNAlig1 and Lig1

DIOPT Version :10

• Sequence 1: NP_611843.2
• Gene: DNAlig1 / 37791
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: NP_034845.3
• Gene: Lig1 / 16881
• MGIID: 101789
• Length: 916
• Species: Mus musculus
• Alignment Length: 760
• Identity: 380/760 - (50%)
• Similarity: 511/760 - (67%)
• Gaps: 42/760 - (5%)

  Fly    10 KKKSDATDSPSPPKKVPKIDAKTELPDEPHIKSESASPETKPKVEPMSVDSEEKTSPVKN----- 69
            :|:.|....||.|.|.|:....|:..:.|..|   |..:.||:.|      |:...|.:.
Mouse   173 EKEGDQLIVPSEPTKSPESVTLTKTENIPVCK---AGVKLKPQEE------EQSKPPARGAKTLS 228

  Fly    70 ---------VKKEPKEVDDKTTDKKVTTIGLNSTAATKEDVENYDPSADSYHPLKNAYWKDKKVT 125
                     ||.|.|:.:..|..|:.|...|        |..||:||.::|||:::|.||..:..
Mouse   229 SFFTPRKPAVKTEVKQEESGTLRKEETKGTL--------DPANYNPSKNNYHPIEDACWKHGQKV 285

  Fly   126 PYLALARTFQVIEETKGRLKMIDTLSNFFCSVMLVSPEDLVPSVYLSINQLAPAYEGLELGVAET 190
            |:||:||||:.|||...||||::||||...||:.:||.||:|.:|||:|:|.|..:||||||.:.
Mouse   286 PFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDG 350

  Fly   191 TLMKAICKATGRNLAHIKSQTQLTGDLGIVAEQSRVSQRMMFQPAPLNVRDVFRKLREIAKLSGQ 255
            .|:||:.:||||.|..|:::....||:|:|||.||.:||:|..|.||.:..||.|..:||:|:|.
Mouse   351 VLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGS 415

  Fly   256 S----KMDLVYNMFVACRSSEARFFIRSLIGKLRIGIAEQSLLTAL--AIGLVKKNH-----IDD 309
            :    |||::..:|||||.||||:..|||.|:||:|:||||:|.||  |:.|.....     :.|
Mouse   416 ASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTAVVD 480

  Fly   310 CKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDIIIPAILKYDIKELQERCPMHPGMPLRPMLAQP 374
            ....|..:..|..:.:..::||..:|:.|:.|.|||.:|::.::.|.|.|.:.||:||:||||.|
Mouse   481 AGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHP 545

  Fly   375 TKGVHEVFERFGGMQITCEWKYDGERAQIHRNEKGEISIFSRNSENNTAKYPDLIARSTALLKGD 439
            |:||.||.:||..:..|||:||||:|||||..|.||:.|||||.|:||.||||:|:|...:....
Mouse   546 TRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGGEVKIFSRNQEDNTGKYPDIISRIPKIKHPS 610

  Fly   440 VKSYIIDSEIVAWDVERKQILPFQVLSTRKRKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSE 504
            |.|:|:|:|.||||.|:|||.|||||:|||||.||..||:||||:|.|||:|:||.:||.:.||.
Mouse   611 VTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSR 675

  Fly   505 RRKLLLEHFQEVEGEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKRSRNW 569
            ||:||.|:|.|.|||:.|.|:|||.|.:::.:|||:|:|.:||||||||||.:|||||||||.||
Mouse   676 RRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNW 740

  Fly   570 LKLKKDYLSNVGDSLDLVVIGGYKGKGRRTGTYGGFLLACYDTENEEYQSICKIGTGFTDEDLQT 634
            ||||||||..|||:|||||||.|.|:|:|.|.|||||||.||.|:||.|:|||:||||:||:|:.
Mouse   741 LKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEE 805

  Fly   635 HSEFLGKHVTSAAKSYYRYDPSLEPDHWFEPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRF 699
            |.:.|...|....:.|.|.|.::.||||.:|..||||||||||||||:.||.|:||.|:||||||
Mouse   806 HHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRF 870

  Fly   700 PRFIRIRDDKNSENATDANQVAHMYQSQDQVKNNQKSSTQMEMED 744
            |||||:|.||..|.||.:||||.:|:.|.|::|.|.|....::||
Mouse   871 PRFIRVRKDKQPEQATTSNQVASLYRKQSQIQNQQSSDLDSDVED 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	380/760 (50%)
Lig1	NP_034845.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..197		8/23 (35%)
		PLN03113	171..912	CDD:215584	378/755 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..266		11/37 (30%)
		Interaction with target DNA. /evidence=ECO:0000250	447..456		5/8 (63%)
		Interaction with target DNA. /evidence=ECO:0000250	640..642		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	879..916		17/37 (46%)