Protein Alignment DNAlig1 and DNAlig1

DIOPT Version :10

• Sequence 1: NP_611843.2
• Gene: DNAlig1 / 37791
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_319999.4
• Gene: DNAlig1 / 1280180
• VectorBaseID: AGAMI1_011198
• Length: 899
• Species: Anopheles gambiae
• Alignment Length: 803
• Identity: 446/803 - (55%)
• Similarity: 555/803 - (69%)
• Gaps: 79/803 - (9%)

  Fly    13 SDATDSPSPPKKVPKIDAKTE-LPDEPHIKS---ESASPETKPKVEP------------------ 55
            |.:::.....|...|.|.|.| ||....:||   ||.:.|||||..|
Mosquito   108 SSSSEDEQDRKATKKSDVKKESLPSPKAVKSEPKESVNKETKPKTSPKKEPASGKEKKEAKKTSP 172

  Fly    56 -----------MSVDSEEKTSPVK--------------------------NVKKEPKEVDDKTTD 83
                       .:|..||..||.|                          :|||:|.|.:.
Mosquito   173 KTTKKSSPKAATTVKKEENPSPTKEKKPSEEKKPDAPAKPTNGAARSFFFSVKKQPDESEG---- 233

  Fly    84 KKVTTIGLNSTAATKEDVENYDPSADSYHPLKNAYWKDKKVTPYLALARTFQVIEETKGRLKMID 148
                  .....|::..|...||||..:|||||:|:||.....||||||||||:||||.|||:||:
Mosquito   234 ------AAGGAASSGNDGSKYDPSKKNYHPLKDAFWKQGDRVPYLALARTFQMIEETSGRLRMIE 292

  Fly   149 TLSNFFCSVMLVSPEDLVPSVYLSINQLAPAYEGLELGVAETTLMKAICKATGRNLAHIKSQTQL 213
            .|||:|.||:|:||.||:.||||.:|||||||||:|||:||.:|||||.::|||:||.||...|.
Mosquito   293 ILSNYFRSVILLSPRDLLASVYLCLNQLAPAYEGVELGIAEFSLMKAIAQSTGRSLAQIKVDAQT 357

  Fly   214 TGDLGIVAEQSRVSQRMMFQPAPLNVRDVFRKLREIAKLSGQS----KMDLVYNMFVACRSSEAR 274
            |||||:|||||:.||.:||:||||:|..||.||||||.::|.:    |||.:.:||||||.||:|
Mosquito   358 TGDLGLVAEQSKSSQHLMFRPAPLSVEVVFGKLREIASMTGSASMAKKMDKIQSMFVACRHSESR 422

  Fly   275 FFIRSLIGKLRIGIAEQSLLTALAIG-LVKKNHID----DCKASKVPDVYKDEIVDTTLLLKTAY 334
            :.||||.||||||:||||||.|||.. .:...|.|    :..|.:.....|..:.:..|.|||.|
Mosquito   423 YIIRSLAGKLRIGVAEQSLLQALAQACALTPPHADPPVVNALAGESEARVKARVDEVALALKTVY 487

  Fly   335 CQCPNYDIIIPAILKYDIKELQERCPMHPGMPLRPMLAQPTKGVHEVFERFGGMQITCEWKYDGE 399
            ||||||:.|:|.:|::.::.|.|.|||.||.||:||||.|||||.||.:||.|:..|||||||||
Mosquito   488 CQCPNYNRIVPVLLEHGVQRLSEHCPMEPGTPLKPMLAHPTKGVQEVLQRFDGIDFTCEWKYDGE 552

  Fly   400 RAQIHRNEKGEISIFSRNSENNTAKYPDLIARSTALLKGDVKSYIIDSEIVAWDVERKQILPFQV 464
            |||||....|.:.|||||.||||:||||:|||........|.|.|:|.|.||||.:::|||||||
Mosquito   553 RAQIHLLADGSVQIFSRNQENNTSKYPDVIARLEFTRTEPVASAILDCEAVAWDTDKRQILPFQV 617

  Fly   465 LSTRKRKNVDIEEIKVQVCVYIFDLLYINGTALVTKNLSERRKLLLEHFQEVEGEWKFATALDTN 529
            |||||||:.:..:|||||||::|||||:||..||.:...|||:||..||:|:||:|::||.|||.
Mosquito   618 LSTRKRKDANEADIKVQVCVFMFDLLYLNGEPLVERPFVERRELLYRHFREIEGQWQYATRLDTG 682

  Fly   530 DIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKRSRNWLKLKKDYLSNVGDSLDLVVIGGYKG 594
            |:||:|:||:|:::|||||||||||..|||||||||||||||||||||:.|||||||||||||:|
Mosquito   683 DLDELQRFLDEAVRGNCEGLMVKTLAREATYEIAKRSRNWLKLKKDYLTGVGDSLDLVVIGGYRG 747

  Fly   595 KGRRTGTYGGFLLACYDTENEEYQSICKIGTGFTDEDLQTHSEFLGKHVTSAAKSYYRYDPSLEP 659
            :|:||||||||||||||.||||||:||||||||:|:|||.|:||...||.:|||.|||::.::.|
Mosquito   748 RGKRTGTYGGFLLACYDEENEEYQTICKIGTGFSDDDLQRHTEFFRSHVIAAAKPYYRHEANVVP 812

  Fly   660 DHWFEPVQVWEVKCADLSLSPIHRAAIGIVDGERGISLRFPRFIRIRDDKNSENATDANQVAHMY 724
            |.||||||||||.||||||||:|||.|||:|.|:|||||||||||:|:||...:||.|.||:.||
Mosquito   813 DDWFEPVQVWEVLCADLSLSPVHRAGIGIIDPEKGISLRFPRFIRVREDKGVTDATSARQVSEMY 877

  Fly   725 QSQDQVKNNQKSSTQMEMEDEFY 747
            .:|||:| ||..|...::|::||
Mosquito   878 LNQDQIK-NQTGSNARDVEEDFY 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	444/799 (56%)
DNAlig1	XP_319999.4	None