Protein Alignment DNAlig1 and DNAlig4

DIOPT Version :10

• Sequence 1: NP_611843.2
• Gene: DNAlig1 / 37791
• FlyBaseID: FBgn0262619
• Length: 747
• Species: Drosophila melanogaster
• Sequence 2: XP_310455.5
• Gene: DNAlig4 / 1271687
• VectorBaseID: AGAMI1_012299
• Length: 914
• Species: Anopheles gambiae
• Alignment Length: 654
• Identity: 151/654 - (23%)
• Similarity: 254/654 - (38%)
• Gaps: 166/654 - (25%)

  Fly   167 PSVYLSINQLAPAYEGLE-----LGVAETTLMKAICKATGRNLAHIKSQTQL---TGDLGIVAEQ 223
            ||::..:..|.|   ||:     .|:.|.:|.:|..:|.|.:......|..|   |.||.
Mosquito    47 PSIHAWLRLLLP---GLDRERKAYGLRERSLAEAYVRALGLDRRSEDVQRLLSAATDDLA----- 103

  Fly   224 SRVSQRMMFQ-PA--PLNVRDVFRKLREIAKLSGQSKMDLVYNMFVACRSSEARFFIRSLIGKLR 285
            :|:...:..: ||  .|.|.||..:|..||.....:....:..:.......:.|:.:|.|:..||
Mosquito   104 TRLGSLLHGRCPAVGDLTVADVNARLDAIADGGPTAARTELVQLIERASPLDQRWLVRILLRNLR 168

  Fly   286 IGIAEQSLLTALAIGLVKKNHIDDCKASKVPDVYKDEIVDTTLLLKTAYCQCPNYDIIIPAILKY 350
            :.::.:.:|        :..|      ...|.:| |...|                      ||.
Mosquito   169 LAVSSRRIL--------QLYH------PSAPTIY-DGASD----------------------LKQ 196

  Fly   351 DIKELQER----------------CPMHPGMPLRPMLAQPTKGVHEVFERFGGMQITCEWKYDGE 399
            .:::::.|                .|:|   .:||||.|..: :.:|.|..|......|.|.|||
Mosquito   197 MVEQIESRQATANELLDEPDGAVIRPLH---FVRPMLCQRLE-LRQVGELLGRDAYWLETKMDGE 257

  Fly   400 RAQIHRNEKGE-ISIFSRNSENNTAKYPDLIARS------------TALLKGDVKSYIIDSEIVA 451
            |.|:|.:  || ...:|||..:    |.:...||            ..||...|:|.::|.|::.
Mosquito   258 RFQVHWD--GETFRYYSRNGHD----YSESFGRSADQVGGTLTPMLATLLAPSVRSLVLDGEMMV 316

  Fly   452 WDVERKQILPFQVLSTRKRKNVDIEEIK--------VQVCVYIFDLLYINGTALVTKNLSERRKL 508
            :|  |:.:        |.|...|..::|        ::.|...:|:|:.||.:|.....:||.:|
Mosquito   317 FD--RRTL--------RYRDKCDGTDVKALRPGNTQLRPCFCAYDVLHHNGRSLAGVPYAERARL 371

  Fly   509 LLEHFQEVEGEWKFATALDTNDIDEVQQFLEESIKGNCEGLMVKTLDEEATYEIAKRS-RNWLKL 572
            |.|..:|..|..:....:...|...:.:.:..:|....||:::|.  |:|.|...:|: ..|.|:
Mosquito   372 LAESVREQFGFLERCRRVRVRDPPHLLELINGAIDERQEGVVLKR--EDAPYRPNRRAGTGWYKI 434

  Fly   573 KKDYLSNVGDSLDLVVIGGYKGKGRRTGTY-GGFL--LACYDTENEEYQSICKIGTGFTDEDLQT 634
            |.||:..:....||:|:||:..:.|   || ..||  :|...|...||.|:.|:..|....:.|.
Mosquito   435 KPDYVDGLVVDFDLLVLGGFYNQRR---TYVNAFLVGVAARTTPRPEYLSVAKVSMGLGTLEWQQ 496

  Fly   635 HSEFLGKHVTSAAKSYYRYDP-------------SLEPDHWFEPVQ--VWEVKCADLSLSPIHRA 684
            .::.|..|        :|..|             ...||.|..|..  ..:::.::|..|..:.|
Mosquito   497 LNQTLRPH--------WRTGPLDGGDGGAVVQCGQTAPDVWIAPADSITLQLRGSELVRSDSYAA 553

  Fly   685 AIGIVDGERGISLRFPRFIRIRDDK---------NSENATDANQVAHMYQSQDQVKNNQKSSTQM 740
                     |.::||||.:.:|.||         ..|....:|:.|.....|...|..::..|
Mosquito   554 ---------GYTIRFPRIVTVRPDKLPDEVCTLDELEQVAGSNRAAPSAGGQRATKLAKRHVT-- 607

  Fly   741 EMED 744
             :||
Mosquito   608 -LED 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig1	NP_611843.2	PLN03113	1..745	CDD:215584	151/654 (23%)
DNAlig4	XP_310455.5	None