DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCP1 and Dcp1b

DIOPT Version :9

Sequence 1:	NP_001163282.1	Gene:	DCP1 / 37790	FlyBaseID:	FBgn0034921	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_008761494.1	Gene:	Dcp1b / 500305	RGDID:	1562214	Length:	605	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	99/338 - (29%)
Similarity:	143/338 - (42%)	Gaps:	43/338 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 MNLAAIKKIDPYAKEIVDSSSHVAFYTFNSSQNEWEKTDVEGAFFIYHRNAEPFHSIFINNRLNT 73
            ::|||:::.|||...|||.:|.||.|||....||||||.|||..|:|.|:|.|.|...|.|||:.
  Rat    16 ISLAALRRHDPYINRIVDVASQVALYTFGHRANEWEKTGVEGTLFVYTRSASPKHGFTIMNRLSM 80

  Fly    74 TSFVEPITGSLELQSQPPFLLYRNERSRIRGFWFYNSEECDRISGLVNGLLKSKD-QGTNGQAQR 137
            .:..||||..|:.|.|.|||||||....|.|.|||:.|||.||:.|:..|.:.:. :..:|....
  Rat    81 ENRTEPITKDLDFQLQDPFLLYRNGTLSIYGIWFYDKEECQRIAKLMKNLTQCEQLKACHGAGAG 145

  Fly   138 HVSAPQQPKQDSSQPASIFNMLTKAQKDYNAQVSGGQPKTPSAENVTAGNVLKFFESAKQATAES 202
              |:|........:...|..|||||:.:|....|..:||..::.:....|.........:.::..
  Rat   146 --SSPVTLSSGEGREVDILQMLTKAKDEYTKCRSCSEPKQMTSSSAICDNPKLIKPVPVRPSSSQ 208

  Fly   203 LFHRVQPLSVDQLEKQQRAAT---------PGEDLLPPAGRDNHESRLSPFQKMQQLNIQLLSDL 258
            ..|...|......|.|....|         |.::.:.|:....|........:.|:
  Rat   209 RLHEPTPSKTLDPEPQHLPLTALFGKQDKAPCQETVKPSRTFAHHHHHHHHHQQQE--------- 264

  Fly   259 KIGKSYATAQSPTVA-PSSSALMANDDAGKCLRRLLAGD------------------KPGPA--L 302
            |:...:..|.|.... |...:|.........:::|:.|.                  .|.||  :
  Rat   265 KLPVHHGVACSLACEDPRKLSLPVEKQLCPAIQKLMVGSMGLHSLPQHPGQWPCESGSPSPAGGI 329

  Fly   303 MP-PTMFDAPNNG 314
            :| |....||.||
  Rat   330 LPGPVQLGAPWNG 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCP1	NP_001163282.1	Dcp1	4..124	CDD:197362	59/114 (52%)
DCP1	NP_001163282.1	mRNA_decap_C	328..362	CDD:293346
Dcp1b	XP_008761494.1	Dcp1	16..131	CDD:197362	59/114 (52%)
Dcp1b	XP_008761494.1	mRNA_decap_C	562..603	CDD:293346
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342307
Domainoid	1	1.000	122	1.000	Domainoid score	I5514
eggNOG	1	0.900	-	-		E1_KOG2868
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1509316at2759
OrthoFinder	1	1.000	-	-		FOG0002778
OrthoInspector	1	1.000	-	-		oto98797
orthoMCL	1	0.900	-	-		OOG6_106417
Panther	1	1.100	-	-	LDO	PTHR16290
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2627
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.710