Protein Alignment PHDP and RHOXF2B

DIOPT Version :10

• Sequence 1: NP_523834.1
• Gene: PHDP / 37788
• FlyBaseID: FBgn0025334
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001093155.1
• Gene: RHOXF2B / 727940
• HGNCID: 33519
• Length: 288
• Species: Homo sapiens
• Alignment Length: 144
• Identity: 42/144 - (29%)
• Similarity: 60/144 - (41%)
• Gaps: 28/144 - (19%)

  Fly    29 NGGGLSVANHINHYNLMIDSSYKLCANESAIRGSLNQESSLLFSKITTVSEFYPATHNIGSYNTD 93
            :|||..|..|:...||           |.......|.|.|       ..||..|...
Human    79 DGGGAGVPGHLWEGNL-----------EGTSGSDGNVEDS-------DQSEKEPGQQ-------- 117

  Fly    94 FHLKSYGDDGLSLTDKSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLHLTEARVQV 158
             :.:..|..|......::|..:. .||..||.|||.||....:|..:.|..:|..:::||..||:
Human   118 -YSRPQGAVGGLEPGNAQQPNVH-AFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQI 180

  Fly   159 WFQNRRAKFRKQER 172
            ||:|||||:|:.:|
Human   181 WFENRRAKWRRHQR 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeodomain	113..169	CDD:459649	23/55 (42%)
RHOXF2B	NP_001093155.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		16/83 (19%)
		Homeodomain	139..191	CDD:459649	23/52 (44%)
		PRK02287	<183..>232	CDD:235024	7/12 (58%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		5/9 (56%)