DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHDP and alx1

DIOPT Version :9

Sequence 1:	NP_523834.1	Gene:	PHDP / 37788	FlyBaseID:	FBgn0025334	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001038539.1	Gene:	alx1 / 565176	ZFINID:	ZDB-GENE-050419-191	Length:	320	Species:	Danio rerio

Alignment Length:	165	Identity:	71/165 - (43%)
Similarity:	95/165 - (57%)	Gaps:	8/165 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NSEFYNSGANGGGLSVANHINHYNLMIDSSYKLCANESAIR--GSLNQESSLLFSKITTVSEFYP 82
            |.::||..:.....:.....|..:..:|.| ..|.|:|::.  ...::||||...:........|
Zfish    31 NVQYYNKASPKCVQAFPMQSNDQHSSMDRS-SPCDNQSSVTYCAPKSEESSLHAMENCCSLRVSP 94

  Fly    83 ATHNIGSYNTDFHLKSYGDDGLSLTDKSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIAS 147
            ||.  |...||  |...|:...|....||:||.||||||.||.||||:|.:|||||:|.||::|.
Zfish    95 ATS--GPDKTD--LDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAM 155

  Fly   148 KLHLTEARVQVWFQNRRAKFRKQERHAIYIMKDKS 182
            :..||||||||||||||||:||:||:. .|.:.||
Zfish   156 RTELTEARVQVWFQNRRAKWRKRERYG-QIQQAKS 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeobox	116..168	CDD:278475	38/51 (75%)
alx1	NP_001038539.1	Homeobox	123..176	CDD:278475	38/52 (73%)
		Transactivation domain. /evidence=ECO:0000250\|UniProtKB:Q63087	180..320		4/11 (36%)
		OAR	296..313	CDD:281777
		OAR. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00138	300..313
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910