Protein Alignment PHDP and PHOX2A

DIOPT Version :9

• Sequence 1: NP_523834.1
• Gene: PHDP / 37788
• FlyBaseID: FBgn0025334
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_005160.2
• Gene: PHOX2A / 401
• HGNCID: 691
• Length: 284
• Species: Homo sapiens
• Alignment Length: 177
• Identity: 73/177 - (41%)
• Similarity: 95/177 - (53%)
• Gaps: 28/177 - (15%)

  Fly     1 MEFSLLNKANFDKDCLYTANSEFYNS-GA--NGGGLSVANHINHYNLMIDSSYKLCANESAIRGS 62
            |::|.||  ::| .|:....:..|.. ||  ..||...:        .:..::..........||
Human     1 MDYSYLN--SYD-SCVAAMEASAYGDFGACSQPGGFQYS--------PLRPAFPAAGPPCPALGS 54

  Fly    63 LNQESSLLFSKITTVSEFYPATHNIGSYNTDFHLKSYGDDGLSLTDKSKQRRIRTTFTSNQLNEL 127
            .|       ..:..:.:..||.::...|       .:..:...|.:|.|||||||||||.||.||
Human    55 SN-------CALGALRDHQPAPYSAVPY-------KFFPEPSGLHEKRKQRRIRTTFTSAQLKEL 105

  Fly   128 EKIFLETHYPDIYTREEIASKLHLTEARVQVWFQNRRAKFRKQERHA 174
            |::|.||||||||||||:|.|:.||||||||||||||||||||||.|
Human   106 ERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAA 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeobox	116..168	CDD:278475	42/51 (82%)
PHOX2A	NP_005160.2	Homeobox	94..147	CDD:365835	43/52 (83%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..284		7/8 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6854
eggNOG	1	0.900	-	-		E1_KOG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1505098at2759
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	1	1.000	-	-		otm40710
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3133
SonicParanoid	1	1.000	-	-		X2223
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.810