DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PHDP and Rx

DIOPT Version :9

Sequence 1:NP_523834.1 Gene:PHDP / 37788 FlyBaseID:FBgn0025334 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_726006.3 Gene:Rx / 37367 FlyBaseID:FBgn0020617 Length:904 Species:Drosophila melanogaster


Alignment Length:152 Identity:65/152 - (42%)
Similarity:86/152 - (56%) Gaps:22/152 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 EFYNSGANGGGLSVANHINHYNLMIDSSYKLCANESAIRGSLNQ-ESSLLFSKITTVSEFYPATH 85
            :|.||| ||.....:|..:|...:...|..|.....|....||| .||....|||:.|:      
  Fly   489 DFRNSG-NGNPNGNSNSGDHGERLNADSDSLVNGSCASSEDLNQTNSSEQGEKITSGSD------ 546

  Fly    86 NIGSYNTDFHLKSYGDDGLSLTDKSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLH 150
            :.|.           ||..:   |.|.||.|||||:.||:|||:.|.::||||:|:|||:|.|::
  Fly   547 DEGQ-----------DDNCA---KKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVN 597

  Fly   151 LTEARVQVWFQNRRAKFRKQER 172
            |.|.||||||||||||:|:||:
  Fly   598 LPEVRVQVWFQNRRAKWRRQEK 619

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PHDPNP_523834.1 Homeobox 116..168 CDD:278475 35/51 (69%)
RxNP_726006.3 Homeobox 563..615 CDD:278475 35/51 (69%)
OAR 876..892 CDD:281777
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 55 1.000 Domainoid score I4097
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000011
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.910

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