Protein Alignment PHDP and pitx2

DIOPT Version :10

• Sequence 1: NP_523834.1
• Gene: PHDP / 37788
• FlyBaseID: FBgn0025334
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_571050.1
• Gene: pitx2 / 30164
• ZFINID: ZDB-GENE-990714-27
• Length: 314
• Species: Danio rerio
• Alignment Length: 148
• Identity: 55/148 - (37%)
• Similarity: 76/148 - (51%)
• Gaps: 24/148 - (16%)

  Fly    26 SGANGGGLSVANHINHYNLMIDSSYKLCANESAIRGSLNQESSLLFSKITTVSEFYPATHNIGSY 90
            :|:....||:|:.:......:||.::|                    .:.|||:    |.:..|.
Zfish    20 TGSKHAPLSMASSLQPLQRSVDSKHRL--------------------DVHTVSD----TSSPESV 60

  Fly    91 NTDFHLKSYGDDGLSLTDKSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLHLTEAR 155
            ..:.......|.....:.|.:|||.||.|||.||.|||..|....|||:.||||||...:|||||
Zfish    61 EKEKGQSKNEDSNDDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 125

  Fly   156 VQVWFQNRRAKFRKQERH 173
            |:|||:|||||:||:||:
Zfish   126 VRVWFKNRRAKWRKRERN 143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeodomain	113..169	CDD:459649	36/55 (65%)
pitx2	NP_571050.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		22/96 (23%)
		Homeodomain	83..139	CDD:459649	36/55 (65%)
		OAR	272..289	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	276..289
		Nuclear localization signal. /evidence=ECO:0000255	282..286