Protein Alignment PHDP and Pax6

DIOPT Version :10

• Sequence 1: NP_523834.1
• Gene: PHDP / 37788
• FlyBaseID: FBgn0025334
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_038655.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Alignment Length: 230
• Identity: 64/230 - (27%)
• Similarity: 99/230 - (43%)
• Gaps: 63/230 - (27%)

  Fly     5 LLNKANFDKDCLYTANSEFYNSG-----ANGGGL------SVANHINHYNLMIDS---------- 48
            :|:..|....|:......:|.:|     |.||..      .|.:.|..|.....|
Mouse    56 VLDNENVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRL 120

  Fly    49 -SYKLCANES---------AIRGSLNQESSL----LFSKIT----------TVSEFYPAT----- 84
             |..:|.|::         .:|...:::..:    ::.|:.          |...:||.|
Mouse   121 LSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQ 185

  Fly    85 --------HNIGSYNTDFHLKSYGDDG----LSLTDKSKQRRIRTTFTSNQLNELEKIFLETHYP 137
                    ...|..||: .:.|.|:|.    :.|..|.|.:|.||:||..|:..|||.|..||||
Mouse   186 PTQDGCQQQEGGGENTN-SISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYP 249

  Fly   138 DIYTREEIASKLHLTEARVQVWFQNRRAKFRKQER 172
            |::.||.:|:|:.|.|||:||||.|||||:|::|:
Mouse   250 DVFARERLAAKIDLPEARIQVWFSNRRAKWRREEK 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeodomain	113..169	CDD:459649	32/55 (58%)
Pax6	NP_038655.1	PAX	4..142	CDD:128645	15/85 (18%)
		Homeodomain	226..281	CDD:459649	32/54 (59%)