DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHDP and Emx1

DIOPT Version :9

Sequence 1:	NP_523834.1	Gene:	PHDP / 37788	FlyBaseID:	FBgn0025334	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_034261.1	Gene:	Emx1 / 13796	MGIID:	95387	Length:	257	Species:	Mus musculus

Alignment Length:	188	Identity:	52/188 - (27%)
Similarity:	88/188 - (46%)	Gaps:	25/188 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SEFYNSGANGGGLSV--------ANHINHYNLMIDSSYKLCANESAIRGSLNQESSLLFSKITTV 77
            |.|..:.|.|.|.|:        ...:||..|.:..:::|.::      ||....|...::....
Mouse    64 SGFPAAAAAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGSS------SLQPPHSFFSAQHRDP 122

  Fly    78 SEFYPATHNIGSYNTDFHLKSYGDDGLSLTD--KSKQRRIRTTFTSNQLNELEKIFLETHYPDIY 140
            ..|||.......:...|.......|||.|..  ..|.:||||.|:.:||..||:.|.:.||....
Mouse   123 LHFYPWVLRNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGA 187

  Fly   141 TREEIASKLHLTEARVQVWFQNRRAKFRKQERHAIYIMKDKSSKLDGRKNPVAGSKYL 198
            .|:::|..|.|:|.:|:|||||||.|:::|:      ::::..:.:.:|.   ||.::
Mouse   188 ERKQLAGSLSLSETQVKVWFQNRRTKYKRQK------LEEEGPESEQKKK---GSHHI 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeobox	116..168	CDD:278475	24/51 (47%)
Emx1	NP_034261.1	COG5576	108..>218	CDD:227863	37/109 (34%)
		Homeobox	163..215	CDD:278475	24/51 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	216..257		4/30 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	66	1.000	Inparanoid score	I5344
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960