DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PHDP and Vsx1

DIOPT Version :9

Sequence 1:	NP_523834.1	Gene:	PHDP / 37788	FlyBaseID:	FBgn0025334	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_473409.1	Gene:	Vsx1 / 114889	MGIID:	1890816	Length:	363	Species:	Mus musculus

Alignment Length:	90	Identity:	45/90 - (50%)
Similarity:	62/90 - (68%)	Gaps:	1/90 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 THNIGSYNTDFHLKSYGDDGLSL-TDKSKQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIAS 147
            :.::.:.:.|...:...|..:|| ..|.|:||.||.||::||.||||.|.|.||||:|.||.:|:
Mouse   142 SESVSTSDGDSPSEEKNDPKMSLILGKRKKRRHRTVFTAHQLEELEKAFGEAHYPDVYAREMLAA 206

  Fly   148 KLHLTEARVQVWFQNRRAKFRKQER 172
            |..|.|.|:||||||||||:||:|:
Mouse   207 KTELPEDRIQVWFQNRRAKWRKREK 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeobox	116..168	CDD:278475	34/51 (67%)
Vsx1	NP_473409.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		Octapeptide motif	31..38
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..66
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	122..166		4/23 (17%)
		Nuclear localization signal. /evidence=ECO:0000255	168..173		2/4 (50%)
		Homeobox	174..227	CDD:278475	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..363
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810