Protein Alignment PHDP and pax6l

DIOPT Version :10

• Sequence 1: NP_523834.1
• Gene: PHDP / 37788
• FlyBaseID: FBgn0025334
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: XP_002938577.1
• Gene: pax6l / 100485335
• XenbaseID: XB-GENE-29077751
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 469
• Identity: 85/469 - (18%)
• Similarity: 153/469 - (32%)
• Gaps: 196/469 - (41%)

  Fly    33 ILVLFP---------------ILTLFGNVLVILAVCRERTLQTVTNYFIVSLAIADLLVAVVVMP 82
            :|.|||               ::.:.||:|.:|.|.|.|.|:|.||.::.|:|.:|||: .:.||
 Frog    34 LLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLI-FLCMP 97

  Fly    83 FAVYVLVSLIHQVNGAWTLPNFACDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIKYAKHKNS 147
            ..   ||.|...  ..|...:..|..:..:...|:.:::..:.|:|::||.|:..|::.......
 Frog    98 LD---LVRLWQY--RPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTK 157

  Fly   148 RRVCLTILLVWAISAAIGSPI--VLGLNNTQDRSP-DLCVFYNTDFIVYSSLTS---------FY 200
            .||.|.|.::||::.....||  ::|:.:.....| |......|:|.|.|.|.:         |:
 Frog   158 GRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFF 222

  Fly   201 IPCIIMVFLYWNIFKALRTRAKKQRAARKPHLSEITAGGSIIENIAQTKRLAETQLDGSTRSGSK 265
            :|...:..||..|.:.|..|
 Frog   223 LPVFCLTVLYSLIGRKLWRR--------------------------------------------- 242

  Fly   266 ILPDEERPTNTASGSNEEDDENAGSPDIDDCHVIVNDKSTEFMLATVVEEAGNVTLKPLSLVRCG 330
                                                                             
 Frog   243 ----------------------------------------------------------------- 242

  Fly   331 VQQALTLNRNDSTLSTNSRDSSRKDKKNTQASRFTIYKVNKASKKKREKSSAKKERKATKTLAIV 395
                   .|.|:.:..:.||.:.|                                :..|.||:|
 Frog   243 -------RRGDAVVGASLRDQNHK--------------------------------QTVKMLAVV 268

  Fly   396 LGVFLFCWVPFFTCNIMDAMCAKLDKDCRPG------VTIF-NLTTW-LGYMNSFVNPVIYTIFN 452
            :..|:.||:||.....:      ..|...||      ::.: ||.:: |.|:::.:||::|.|.:
 Frog   269 VFAFILCWLPFHVGRYL------FSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMS 327

  Fly   453 PEFRKAFKKIMHIE 466
            .::|.|..:::..|
 Frog   328 KKYRVAVFRLLGFE 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHDP	NP_523834.1	Homeodomain	113..169	CDD:459649	15/57 (26%)
pax6l	XP_002938577.1	Homeodomain	78..133	CDD:459649	15/60 (25%)