Protein Alignment TM4SF and Tsp86D

DIOPT Version :10

• Sequence 1: NP_001261159.1
• Gene: TM4SF / 37786
• FlyBaseID: FBgn0020372
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_001262468.1
• Gene: Tsp86D / 41310
• FlyBaseID: FBgn0037848
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 53/267 - (19%)
• Similarity: 95/267 - (35%)
• Gaps: 74/267 - (27%)

  Fly     9 CFKYLVYSYVVLLALTGAAQIFLGT-----SLLWGH-----SVYYGIVQNKLWAPAAILLCLGPV 63
            |.||:::....|..|.|...:.:|.     .|:.|:     ...|.::.|    .:.:::..|.:
  Fly    30 CVKYMIFLLNFLFWLFGGLLLAIGVYAFMDKLMDGNGWLRLDTIYDVIFN----ISLVMIIAGVI 90

  Fly    64 TFILCWMGCQATNQRKRCLLGMFAALL---------VACICVQFIICGWSLAMRENLPTSVEIFI 119
            .|.:.:.||....:....||.:::..|         :|.||..|             |..:..|:
  Fly    91 VFTVSFAGCLGALRENTWLLKLYSMCLLLFFILEMSLAIICFVF-------------PQYMNSFL 142

  Fly   120 DDSFVEFLDKFSRTKVDNLHLWNRM---QSQLQCCGVD--GPLDY-------------RRLSLPW 166
            :   .:|.||...:..|:..|.|.:   |.:..|||:.  |..|:             .|..:|:
  Fly   143 E---YQFTDKIIHSYRDDSDLQNFIDFAQQEFNCCGLSNAGYQDWSKNEYFNCSSPSVERCGVPY 204

  Fly   167 SCCSRPE-----------------HAYESACDTHYKRGCLAVVSEQIRNRLLITAFGAAIIAIFQ 214
            |||....                 .:..:|....:..||:.:|...:...|.:.|..|..||:.|
  Fly   205 SCCINATDISSGLVNIMCGYGVQVRSVAAASKRIWTSGCIEIVRVWVERNLYVIAGVALGIALLQ 269

  Fly   215 SLGIFCA 221
            ...|:.|
  Fly   270 LFVIYLA 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM4SF	NP_001261159.1	Tetraspanin	10..224	CDD:459767	52/266 (20%)
Tsp86D	NP_001262468.1	Tetraspanin	51..279	CDD:459767	47/246 (19%)
		penumbra_like_LEL	132..255	CDD:239411	24/138 (17%)