DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ken and cbt

DIOPT Version :9

Sequence 1:NP_523833.1 Gene:ken / 37785 FlyBaseID:FBgn0011236 Length:601 Species:Drosophila melanogaster
Sequence 2:NP_722636.1 Gene:cbt / 33224 FlyBaseID:FBgn0043364 Length:428 Species:Drosophila melanogaster


Alignment Length:367 Identity:73/367 - (19%)
Similarity:125/367 - (34%) Gaps:94/367 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   281 LDLRTKSENSASRTLGSGSDHSGIDLAVTASESTKRKGLFFDSHKDVMKPLSDGSDINSSPENYV 345
            |::..|.|...:..|....      |.:.|.:|.|..|:...:..|..         :.:||  :
  Fly    21 LEIVAKDEQQVNENLLKAK------LKLVAQKSQKNGGIITPNPSDTE---------DEAPE--I 68

  Fly   346 VTPHRKRR---PGFHNTQSDNQPFTSYPHSLLEELRLAKSTTSPISGFGSEKNMLAHLE--DGAL 405
            ..|::|.|   |....|...:|.......:....:.:..:::..:|....::|..:...  ..:.
  Fly    69 AVPNKKPRLEQPAMSMTPPPDQKLDDDQKAERVSVIMRVNSSGAVSSSSQDENSSSSTSCCSSSS 133

  Fly   406 NGDTLTP-----------------------DRKHLLEAQRNRAQSPEIPMH-------------- 433
            |.:|.|.                       :||...|......|:||.|:.              
  Fly   134 NTNTSTSSVPPTVEDDYPEANVWRNLKFKMNRKRAAEVALPPVQTPETPVAKLVTPPAPAECIKE 198

  Fly   434 ------LGPQFVYQWQSNQNAAMSAMPNLQSRLSSLSHISLNLDH---PEGRSGSASGSGANLAG 489
                  |.|.:|           |.:.:..|:|..||.::.....   |:..:.|.......:..
  Fly   199 EEIKPILTPIYV-----------SPVASSASQLILLSTVAAQQSPTPVPKTPTMSEEKLTTRITA 252

  Fly   490 SNTHASSVREYRCEY--CGKQFGMSWNLKTHLRVHTGEKPFACRL--CVAMFKQKAHLLKHLCSV 550
            :...|:..|.|.|.:  |||.:..|.:||.|.||||||:||.|:.  |...|.:...|.:|.   
  Fly   253 AQAAATRSRIYECSFPDCGKNYFKSSHLKAHQRVHTGERPFICKWENCDKRFSRSDELSRHK--- 314

  Fly   551 HRNVITTTNGADTENRYSCCFCSMCFESVQELVRHLSGHHNN 592
                 .|..|   |.::.|..|...|.....|.:|:..|:.:
  Fly   315 -----RTHTG---EKKFQCSVCQKKFMRSDHLSKHVKRHNKD 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kenNP_523833.1 BTB 27..>107 CDD:279045
BTB 34..>107 CDD:197585
zf-C2H2 500..522 CDD:278523 10/23 (43%)
C2H2 Zn finger 502..522 CDD:275368 9/21 (43%)
zf-H2C2_2 514..539 CDD:290200 14/26 (54%)
C2H2 Zn finger 530..551 CDD:275368 5/22 (23%)
C2H2 Zn finger 569..589 CDD:275368 5/19 (26%)
cbtNP_722636.1 zf-C2H2 263..287 CDD:278523 10/23 (43%)
C2H2 Zn finger 265..287 CDD:275368 9/21 (43%)
COG5048 <270..362 CDD:227381 29/90 (32%)
zf-H2C2_2 279..306 CDD:290200 14/26 (54%)
C2H2 Zn finger 295..317 CDD:275368 5/29 (17%)
zf-H2C2_2 309..332 CDD:290200 7/33 (21%)
zf-C2H2 323..345 CDD:278523 5/21 (24%)
C2H2 Zn finger 325..345 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S4872
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.950

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