DRSC/TRiP Functional Genomics Resources

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Protein Alignment ken and Bcl11b

DIOPT Version :9

Sequence 1:NP_523833.1 Gene:ken / 37785 FlyBaseID:FBgn0011236 Length:601 Species:Drosophila melanogaster
Sequence 2:XP_038968327.1 Gene:Bcl11b / 314423 RGDID:1311128 Length:884 Species:Rattus norvegicus


Alignment Length:480 Identity:104/480 - (21%)
Similarity:157/480 - (32%) Gaps:129/480 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   185 CESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNISTSSNHQQQQ 249
            |..|::.:|   |....      .||.......:|:.::.:::|..|||....::..:..     
  Rat   463 CSQASKLKR---HMKTH------MHKAGSLAGRSDDGLSAASSPEPGTSELPGDLKAADG----- 513

  Fly   250 HHHHHHHNHNNNNNNNNNNSSSSTINPVNLSLDLRTKSENSASRTLGSGSDH----------SGI 304
            ...||..:.:......::.........:.|..:.|.:|..|....||.|.::          :|.
  Rat   514 DFRHHESDPSLGPEPEDDEDEEEEEEELLLENESRPESSFSMDSELGRGRENGGGVPPGVAGAGA 578

  Fly   305 DLAVTASEST-------------------KRKGLFFDSHKDVMKPLSDGSDINSSPENYVVTPHR 350
            ..|..|.|..                   :::|.|       :|...|..|..:........|..
  Rat   579 AAAALADEKALALGKVMEDAGLGALPQYGEKRGAF-------LKRAGDAGDTGAGGCGDAGAPGA 636

  Fly   351 KR------RPGFHNTQSDNQPFTS-YPHSLLEELRLAKSTTSPISGFGSEKNMLAHLEDGALNGD 408
            ..      .||       .:||.: :|.         |....|..|.|               |.
  Rat   637 VNGRGGAFAPG-------AEPFPALFPR---------KPAPLPSPGLG---------------GP 670

  Fly   409 TLTPDRKHLLEAQRNRAQSPEIPMHLGPQFVY-QWQSNQNAAMSAM-------------PNLQSR 459
            .|...::..:|.......:..||    .:.|| ||.....|:...|             |...|.
  Rat   671 ALHAAKRIKVEKDLELPPAALIP----SENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSS 731

  Fly   460 LSSLSHISLNLDHP---------EGRSGSAS-GSGANLAGSNTHASSVREYR----CEYCGKQFG 510
            ..|..:.||....|         .||||:|| ||..:|.|......|.:|.|    ||||||.|.
  Rat   732 EHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLGGPGPGRPSSKEGRRSDTCEYCGKVFK 796

  Fly   511 MSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGADTENRYSCCFCSMC 575
            ...||..|.|.||||:|:.|.||.....|.:.|.:|:         .|:|...:..|.|..|.|.
  Rat   797 NCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHM---------KTHGQIGKEVYRCDICQMP 852

  Fly   576 FESVQELVRHLSGHHNNLLLTKNLR 600
            |.....|.:|:...|...|||.:::
  Rat   853 FSVYSTLEKHMKKWHGEHLLTNDVK 877

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kenNP_523833.1 BTB 27..>107 CDD:279045
BTB 34..>107 CDD:197585
zf-C2H2 500..522 CDD:278523 12/25 (48%)
C2H2 Zn finger 502..522 CDD:275368 11/19 (58%)
zf-H2C2_2 514..539 CDD:290200 12/24 (50%)
C2H2 Zn finger 530..551 CDD:275368 6/20 (30%)
C2H2 Zn finger 569..589 CDD:275368 6/19 (32%)
Bcl11bXP_038968327.1 zf-C2H2 427..448 CDD:395048
C2H2 Zn finger 428..448 CDD:275370
zf-H2C2_2 440..465 CDD:404364 1/1 (100%)
C2H2 Zn finger 456..476 CDD:275370 4/15 (27%)
zf-C2H2 787..808 CDD:395048 11/20 (55%)
C2H2 Zn finger 788..808 CDD:275368 11/19 (58%)
zf-H2C2_2 800..825 CDD:404364 12/24 (50%)
C2H2 Zn finger 816..836 CDD:275368 6/28 (21%)
C2H2 Zn finger 846..864 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45993
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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