DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ken and zbtb46

DIOPT Version :10

Sequence 1:NP_523833.1 Gene:ken / 37785 FlyBaseID:FBgn0011236 Length:601 Species:Drosophila melanogaster
Sequence 2:XP_031750218.1 Gene:zbtb46 / 100145588 XenbaseID:XB-GENE-5847062 Length:572 Species:Xenopus tropicalis


Alignment Length:643 Identity:126/643 - (19%)
Similarity:208/643 - (32%) Gaps:230/643 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCSTT 74
            ::...|...:|:|:....:.....|..|:.|.|: ..|||.||..:|...:.|......:...||
 Frog     8 MEIPSHYRRLLQELNEQRQHGILCDACIIVEGKI-FKAHKNVLLGSSRYFKTLYCQVQKAAEPTT 71

  Fly    75 VYFPD-VNATYFKFLLDFLYSGQTCITSRDV-------NYL---------HDLL---LLLQIKSD 119
            |...| |.|..||.::||:||....:||::|       :||         |..:   |.:.||||
 Frog    72 VTQLDIVTAQGFKAIIDFMYSAHLALTSKNVIEVMSAASYLQMTDIVQACHGFIKAALDISIKSD 136

  Fly   120 SWKTTD----------SAYLSSKCGG--LRDRADRRKQQYTSPQNLEPDQTL--------KYEVD 164
            . :.||          .|.||:...|  :.....||    |||.|...|..:        .|..:
 Frog   137 D-ELTDYDMGAPSGSAEALLSAVVAGRSISPWLARR----TSPANSSGDSAIASCHEGGSSYGKE 196

  Fly   165 SVDESRNAADFSSAFNSNDNC--------------ESAAECERSGGHNNKEEDEDDCTHKDNKSD 215
            ..::..::.|..||..:.|.|              ..|.:.|..|.:..:.:.......:.|:.:
 Frog   197 DPEQKGDSQDEGSAVWAGDMCYGPLRIKEEQDSPGRYAGKGEAGGSYLEQGDGWQHSGRRKNRKN 261

  Fly   216 KDTDEIVNLSNAPPSGTSGSNSNISTSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSSTINPVNLS 280
            |:|...:.........|.....:..:||     |.|:         :|.:|::...:.|.|    
 Frog   262 KETVRHITQQMVESCRTGSPEPSFISSS-----QWHY---------SNQDNSSDEVTVIEP---- 308

  Fly   281 LDLRTKSENSASRTLGSGSDHSGIDLAVTASESTKRKGLFFDSHKDVMKPLSDGSDINSSPENYV 345
                             ||.                     ||.::.:...|.|.:         
 Frog   309 -----------------GSS---------------------DSREERVDLYSQGEE--------- 326

  Fly   346 VTPHRKRRPGFHNTQSDNQPFTSYPHSLLEELRLAKSTTSPISGFGSEKNMLAHLEDGALNGDTL 410
                        :.|.....:..:|.||.:|           .|.|...|:              
 Frog   327 ------------SLQGGEATYLPHPLSLEKE-----------EGHGQVTNL-------------- 354

  Fly   411 TPDRKHLLEAQRNRAQSPEIPMHLGPQFVYQWQSNQNAAMSAMPNLQSRLSSLSHISLNLDHPEG 475
               |..||                          ::|:.::...::....|||....|    |:|
 Frog   355 ---RSALL--------------------------SKNSLLALKADVLGEESSLLFEYL----PKG 386

  Fly   476 RSGSASGSGANLAGSNTHASSVRE-------YRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLC 533
                            ||:.|:.|       ::|.||.........||.|:|.||||:|:.|.:|
 Frog   387 ----------------THSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEIC 435

  Fly   534 VAMFKQKAHLLKHLCSVHRNVITTTNGADTENRYSCCFCSMCFESVQEL-VRHLSGHH 590
            ...|.::.|:.:|.. ||          ..:.:|.|..|:..|.|...: ::|.|..|
 Frog   436 GKKFTRREHMKRHTL-VH----------SKDKKYVCKVCNRVFMSAASVGIKHGSRRH 482

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kenNP_523833.1 BTB_POZ_BAB-like 32..117 CDD:349624 30/104 (29%)
zf-C2H2 500..522 CDD:395048 7/21 (33%)
C2H2 Zn finger 502..522 CDD:275368 7/19 (37%)
zf-H2C2_2 514..539 CDD:463886 12/24 (50%)
C2H2 Zn finger 530..551 CDD:275368 5/20 (25%)
C2H2 Zn finger 569..589 CDD:275368 6/20 (30%)
zbtb46XP_031750218.1 BTB_POZ 10..134 CDD:453885 33/124 (27%)
COG5048 <258..>465 CDD:227381 62/368 (17%)
zf-H2C2_5 402..426 CDD:404746 8/23 (35%)
C2H2 Zn finger 404..424 CDD:275368 7/19 (37%)
zf-H2C2_2 417..441 CDD:463886 12/23 (52%)
C2H2 Zn finger 432..452 CDD:275368 5/20 (25%)
C2H2 Zn finger 460..482 CDD:275368 6/21 (29%)

Return to query results.
Submit another query.