Protein Alignment Mtpbeta and ACAA1

DIOPT Version :9

• Sequence 1: NP_477378.1
• Gene: Mtpbeta / 37784
• FlyBaseID: FBgn0025352
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001598.1
• Gene: ACAA1 / 30
• HGNCID: 82
• Length: 424
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 147/440 - (33%)
• Similarity: 214/440 - (48%)
• Gaps: 60/440 - (13%)

  Fly    38 QKNSQNIVLVDGVRTPFLTSGT-TYSKLMPHELARHSLLSLLQKNRLDKELIDYIVYGSVIQEVK 101
            |.::.::|:|.|.||....:|. .:....|.||....:.::|:...|..|.:..|..|:|:|...
Human    32 QASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGA 96

  Fly   102 TSNIAREAALAAGFSNKTPAHTVTMACISSNAAITTGMGLIATNTYDVIVAGGVEFMSDVPIRHS 166
            .:.:||.|...:......|..||...|.|...|:.:..|.|...:||:.:|.|||.||.....:.
Human    97 GAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNP 161

  Fly   167 RKMRSLLLKANKAKTLGQRLALLSTFRPDFLAPELPAVAEFSSGETMGHSADRLASAFNVSRSEQ 231
            ..:.|.|::..||:              |.|.|             ||.:::.:|..|.:||.:|
Human   162 GNITSRLMEKEKAR--------------DCLIP-------------MGITSENVAERFGISREKQ 199

  Fly   232 DEYALRSHTLAKEAQEKGYF-TDLVPFKVSGVDQ-------IVDKDNGIRVSSP-ESLAKLRPAF 287
            |.:||.|...|..||.||.| .::||...:..|.       .|.:|.|||.|:. |.||||:|||
Human   200 DTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF 264

  Fly   288 VKPYGTVTAANASFLTDGASACIIMTEEKAKQLGLKPKAYLRDFLFVSQDPVNQLLLGPAYGIPK 352
            .|. |:.||.|:|.::|||:|.::....||::|||.....||.:..|...| :.:.:||||.||.
Human   265 KKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPP-DIMGIGPAYAIPV 327

  Fly   353 LLKKAGLTLKDIDSWEIHEAFAGQIVANLKALDSDWFCKTYLGLNEKVGTPDLSKWNNWGGSLSI 417
            .|:|||||:.|:|.:||:||||.|..          :|.      ||:..|. .|.|..||::::
Human   328 ALQKAGLTVSDVDIFEINEAFASQAA----------YCV------EKLRLPP-EKVNPLGGAVAL 375

  Fly   418 GHPFAATGVRLCMHTANRLVREDGK--LGVVAACAAGGQGVAMLIERYPG 465
            |||...||.|..:...|.|.|. ||  .|||:.|...|.|.|.:.| |||
Human   376 GHPLGCTGARQVITLLNELKRR-GKRAYGVVSMCIGTGMGAAAVFE-YPG 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtpbeta	NP_477378.1	fadI	44..462	CDD:181597	142/429 (33%)
		thiolase	45..462	CDD:238383	142/428 (33%)
ACAA1	NP_001598.1	Thiolase_N	1..420	CDD:332572	143/434 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820