Protein Alignment Mtpbeta and Acat1

DIOPT Version :9

• Sequence 1: NP_477378.1
• Gene: Mtpbeta / 37784
• FlyBaseID: FBgn0025352
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_659033.1
• Gene: Acat1 / 110446
• MGIID: 87870
• Length: 424
• Species: Mus musculus
• Alignment Length: 477
• Identity: 152/477 - (31%)
• Similarity: 233/477 - (48%)
• Gaps: 73/477 - (15%)

  Fly     1 MSLQNVCRKGNAFNLLNVARKVQCRALSAAVANPQPKQKNSQNIVLVDGVRTPFLTSGTTYSKLM 65
            ::|..|.|:.....||   ::|:|...|.|      .:.....:|:|..:|||.   |:....|.
Mouse     5 VALHGVVRRPLLRGLL---QEVRCLERSYA------SKPTLNEVVIVSAIRTPI---GSFLGSLA 57

  Fly    66 PH---ELARHSLLSLLQKNRLDKELIDYIVYGSVIQEVKTSNIAREAALAAGFSNKTPAHTVTMA 127
            ..   :|...::...::|..:.||.:..:..|:|||..:.....|:|.|.||....||..||...
Mouse    58 SQPATKLGTAAIQGAIEKAGIPKEEVKEVYMGNVIQGGEGQAPTRQATLGAGLPISTPCTTVNKV 122

  Fly   128 CISSNAAITTGMGLIATNTYDVIVAGGVEFMSDVPIRHSR--------KMRSLLLKANKAKTLGQ 184
            |.|...||......:.....||:||||:|.||:||...||        |:..|::|
Mouse   123 CASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMSRGATPYGGVKLEDLIVK--------- 178

  Fly   185 RLALLSTFRPDFLAPELPAVAEFSSGETMGHSADRLASAFNVSRSEQDEYALRSHTLAKEAQEKG 249
                             ..:.:..:...||:.|:..|...|:||.|||.|||.|:|.:|||.:.|
Mouse   179 -----------------DGLTDVYNKIHMGNCAENTAKKMNISRQEQDTYALSSYTRSKEAWDAG 226

  Fly   250 YF-TDLVPFKVS---GVDQIVDKDNGIRVSSPESLAKLRPAFVKPYGTVTAANASFLTDGASACI 310
            .| :::.|..:|   ..|.:|.:|...:......:.||:..|.|..||:||||||.|.|||:|.:
Mouse   227 KFASEITPITISVKGKPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTITAANASTLNDGAAALV 291

  Fly   311 IMTEEKAKQLGLKPKAYLRDFLFVSQDPVNQLLLGPAYGIPKLLKKAGLTLKDIDSWEIHEAFAG 375
            :||.|.|::|.:||.|.:..|...:.||:: ..|.|||.:||:||.|||..:||..||::|||:.
Mouse   292 LMTAEAAQRLNVKPLARIAAFADAAVDPID-FPLAPAYAVPKVLKYAGLKKEDIAMWEVNEAFSV 355

  Fly   376 QIVANLKALDSDWFCKTYLGLNEKVGTPDLSKWNNWGGSLSIGHPFAATGVRLCMHTANRLVRED 440
            .::||:|.|:.|               |  .|.|..||::|:|||...:|.|:.:|.|:.|  :.
Mouse   356 VVLANIKMLEID---------------P--QKVNIHGGAVSLGHPIGMSGARIVVHMAHAL--KP 401

  Fly   441 GKLGVVAACAAGGQGVAMLIER 462
            |:.|:.:.|..||...|:|||:
Mouse   402 GEFGLASICNGGGGASALLIEK 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtpbeta	NP_477378.1	fadI	44..462	CDD:181597	142/432 (33%)
		thiolase	45..462	CDD:238383	142/431 (33%)
Acat1	NP_659033.1	PLN02644	38..424	CDD:215347	143/435 (33%)
		thiolase	40..423	CDD:238383	142/431 (33%)
		Coenzyme A binding. /evidence=ECO:0000250|UniProtKB:P24752	255..257		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810