Protein Alignment TBPH and NOP4

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_015282.1
• Gene: NOP4 / 856063
• SGDID: S000005964
• Length: 685
• Species: Saccharomyces cerevisiae
• Alignment Length: 296
• Identity: 65/296 - (21%)
• Similarity: 97/296 - (32%)
• Gaps: 100/296 - (33%)

  Fly    79 PKEN-KRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDT 142
            |..| .:::||.|:..|              |.|..:|...|:|.|.::|..:..:..|.:.|||
Yeast    11 PSSNVSKQNDDGLDMKT--------------LFVRSIPQDVTDEQLADFFSNFAPIKHAVVVKDT 61

  Fly   143 KSGQSKGFGFVRFGSYDAQMRVLT-------NRHLI-------------DGRWCEVKVPNSKGMG 187
            .. :|:|||||.|...|.....|.       |.|::             .....|...|.|.
Yeast    62 NK-RSRGFGFVSFAVEDDTKEALAKARKTKFNGHILRVDIAKRRDRSKKTSEVVEKSTPESS--- 122

  Fly   188 HQVPCKVFVGRCTEDINSDD--------------------------LREYFSKFGEVTDVFIPR- 225
                 :...|:..||.:..|                          |::.|.::|.|.:..|||
Yeast   123 -----EKITGQNNEDEDDADGEDSMLKGKPKLIIRNMPWSCRDPVKLKKIFGRYGTVVEATIPRK 182

  Fly   226 ---PFRAFSFVTFLDPDVAQSLC------GEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSA 281
               ....|:|||.    ...|.|      .:|..|.|..|.|..|..|   ||.:     :|..|
Yeast   183 RDGKLCGFAFVTM----KKISNCRIALENTKDLKIDGRKVAVDFAVQK---NRWE-----DYKKA 235

  Fly   282 NSFGMHSYHPQGNHMNPGRNGHHRGNNQHNAHGGEN 317
                    .|:.|..:...:|:......|:....||
Yeast   236 --------QPEMNDKDDNESGNEDAEENHDDEEDEN 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	23/92 (25%)
		RRM2_TDP43	192..261	CDD:409761	22/104 (21%)
NOP4	NP_015282.1	RRM1_Nop4p	26..104	CDD:410075	23/92 (25%)
		RRM2_Nop4p	147..229	CDD:410076	21/88 (24%)
		RRM3_Nop4p	289..387	CDD:410077
		RRM4_Nop4p	458..620	CDD:410078