Protein Alignment TBPH and PHIP1

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_191094.1
• Gene: PHIP1 / 824700
• AraportID: AT3G55340
• Length: 597
• Species: Arabidopsis thaliana
• Alignment Length: 538
• Identity: 110/538 - (20%)
• Similarity: 187/538 - (34%)
• Gaps: 161/538 - (29%)

  Fly     2 DFVQVSEEEGDEPIELPAEEDGTLLLSTLQAQFPGSCGLKYRNLDTKAVRGVRSNEGRLFPPSVE 66
            |.|:|.|.||||              .|.:.|.|    .|.:|...|..|.|...     |...|
plant    92 DAVEVDELEGDE--------------GTKEEQKP----QKKKNKKKKKKRKVNKT-----PKKAE 133

  Fly    67 SGWGEYAYFCVFPKENKRKSDDNLENSTAKTKRIETRLRCTDLIVLGLPWKTTEESLREYFETYG 131
            .|..|..   |..:|.:..:|:..|:.....|          |.|.|:|:::||:.:|.||.:.|
plant   134 EGNVEEK---VKVEEIEVNTDNKEEDGVVPNK----------LYVGGIPYQSTEDEIRSYFRSCG 185

  Fly   132 EVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLT-------NRHLIDGRWCEVKVPN------S 183
            .::....|...:.|...|..|:.|.:.|...|.|.       :|:|...::.:...|:      |
plant   186 VIIKVDCKMRPEDGAFSGIAFITFDTEDGAKRALAFDRAAMGDRYLTIQQYVKTTTPSIPRRKTS 250

  Fly   184 KGMGHQVP---CKVFVGRCTEDINSDDLREYFS-------KFGEVTDVFIPRPFRAFSFVTFLDP 238
            .|...::.   .:|::|....|....|:|:.||       :.|:..:.   ..|:.::.|.|.|.
plant   251 SGFAPEMVDGYNRVYIGNLAWDTTERDIRKLFSDCVINSVRLGKNKET---GEFKGYAHVDFKDS 312

  Fly   239 -DVAQSLCGEDHIIKGVSVHVSNA---APKAEQNRNQQVQSYNYNSANSFGMHSYHP-------- 291
             .||.:|..:..:|.|..|.:..|   .|..:....:...:.:||..:::......|
plant   313 VSVAIALKLDQQVICGRPVKICCALKDRPATDHTPGETNNAGSYNMEDTYAAADPVPALAGRSEV 377

  Fly   292 -QGNHM---------------NPGRNGH---------HRGNNQHNAHGGENAIVPNNHNIGTAGY 331
             .||:.               ..|..||         .:.::|.|:..|:..:   :.......|
plant   378 DDGNYFATTVSSSKVKRRVCYECGEKGHLSTACPIKLQKADDQANSKLGQETV---DGRPAMQSY 439

  Fly   332 GMGGNNYGGNSGGGYHNNGGNHSSGGNTNRQDGGSQYNSRQSNFHGMNQPHNGNVGGS---NGWM 393
            |:     ..|||..|:.|                       ..:...|:.:||....|   .|.:
plant   440 GL-----PKNSGDSYYMN-----------------------ETYASTNETYNGGYSASAVGTGKV 476

  Fly   394 NR---------GHLDMPNLQALGINSQGSSSSNQGQNMSNQSMLNLNSLPINPALVAAALNQWSL 449
            .|         |||.    .|..|..|.:|.:|        |.|:..::...|..|.:    :||
plant   477 KRRNCYECGEKGHLS----TACPIKLQNTSHTN--------STLDHQTVEAGPTQVTS----YSL 525

  Fly   450 VGNQLQNQNQDQQGGNFL 467
               |.:.::.:..||:|:
plant   526 ---QKKTRDTENNGGSFM 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	19/74 (26%)
		RRM1_TDP43	108..181	CDD:409760	20/79 (25%)
		RRM2_TDP43	192..261	CDD:409761	18/76 (24%)
PHIP1	NP_191094.1	RRM1_PHIP1	163..234	CDD:409714	20/70 (29%)
		RRM2_PHIP1	263..334	CDD:409715	18/73 (25%)
		PTZ00368	393..592	CDD:173561	37/198 (19%)