Protein Alignment TBPH and Hnrnpd

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_077380.2
• Gene: Hnrnpd / 79256
• RGDID: 620365
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 310
• Identity: 85/310 - (27%)
• Similarity: 138/310 - (44%)
• Gaps: 34/310 - (10%)

  Fly    82 NKRKSDDNLENSTAKTKRIETRLRCT-DLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSG 145
            :|.:.|:...||:.:.....|..|.. .:.:.||.|.||::.|::||..:|:|:...:|.|..:|
  Rat    69 SKNEEDEGHSNSSPRHTEAATAQREEWKMFIGGLSWDTTKKDLKDYFSKFGDVVDCTLKLDPITG 133

  Fly   146 QSKGFGFVRFGSYDAQMRVLTNR-HLIDGRWCEVKVPNSKGMGHQVPC-KVFVGRCTEDINSDDL 208
            :|:|||||.|...::..:|:..: |.::|:..:.|  .:|.|..:.|. |:|||..:.|...:.:
  Rat   134 RSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPK--RAKAMKTKEPVKKIFVGGLSPDTPEEKI 196

  Fly   209 REYFSKFGEVTDVFIP-----RPFRAFSFVTFLDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQN 268
            ||||..||||..:.:|     ...|.|.|:||.:.:..:.:..:    |..:|.:|....|...:
  Rat   197 REYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEK----KYHNVGLSKCEIKVAMS 257

  Fly   269 RNQQVQSYNYNSANSFGMHSYHPQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGM 333
            :.|..|...:.|...|.             ||.....|....|.:.|.:    |..|.|...||.
  Rat   258 KEQYQQQQQWGSRGGFA-------------GRARGRGGGPSQNWNQGYS----NYWNQGYGSYGY 305

  Fly   334 GGNNYGGNSGGGYHNNGGNHSSG-GNTNRQDGGSQYNSRQSNFHGMNQPH 382
            ....|||.  |||...|.|...| |:.:.|..|....||:.......:|:
  Rat   306 NSQGYGGY--GGYDYTGYNSYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	24/73 (33%)
		RRM2_TDP43	192..261	CDD:409761	22/74 (30%)
Hnrnpd	NP_077380.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..89		4/19 (21%)
		CBFNT	<55..76	CDD:311868	2/6 (33%)
		RRM1_hnRNPD	97..170	CDD:410150	24/74 (32%)
		RRM2_hnRNPD	181..255	CDD:241027	23/77 (30%)