Protein Alignment TBPH and ncl

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001070120.3
• Gene: ncl / 767714
• ZFINID: ZDB-GENE-030131-6986
• Length: 704
• Species: Danio rerio
• Alignment Length: 304
• Identity: 67/304 - (22%)
• Similarity: 100/304 - (32%)
• Gaps: 92/304 - (30%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNRHLIDG 173
            |:|..|.:..:|:||:..||....:.:.|     .:|:.||:.||.|.:.:.....|.|.:..|.
Zfish   466 LVVNNLAFSASEDSLQSVFEKAVSIRIPQ-----NNGRPKGYAFVEFENVEDSKEALENCNNTDI 525

  Fly   174 RWCEVKVPNSK--------GMGHQVPCK-VFVGRCTEDINSDDLREYF-----SKFGEVTDVFIP 224
            ....:::..|:        |.|:..|.| :||...::|.....|::.|     ::.....|.
Zfish   526 EGRSIRLEYSQNDRERGGGGRGNSGPTKTLFVKGLSDDTTDQTLKDSFDGAIAARIATDRDT--- 587

  Fly   225 RPFRAFSFVTF---LDPDVAQSLCGEDHIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGM 286
            ...:.|.||.|   .|...|:... :|..|.|..|.:..|.||.|
Zfish   588 GSSKGFGFVDFDNEQDCKAAKEAM-DDGEIDGNKVTLDYAKPKGE-------------------- 631

  Fly   287 HSYHPQGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGGNSGGGYHNNGG 351
                       .||.|...|.......||           |..|:|..|   ||..|||:....|
Zfish   632 -----------GGRGGFGGGRGGFGGRGG-----------GRGGFGGRG---GGGRGGGFRGGRG 671

  Fly   352 NHSSGGNTNRQDGGSQYNSRQSNFHGMNQPHNGNVGGSNGWMNR 395
            ....||......||                     ||..|:.:|
Zfish   672 GRGGGGGFRGGRGG---------------------GGRGGFGDR 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	18/71 (25%)
		RRM2_TDP43	192..261	CDD:409761	17/77 (22%)
ncl	NP_001070120.3	None