Protein Alignment TBPH and hnrnpa3

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001315077.1
• Gene: hnrnpa3 / 751729
• ZFINID: ZDB-GENE-060224-1
• Length: 340
• Species: Danio rerio
• Alignment Length: 310
• Identity: 102/310 - (32%)
• Similarity: 136/310 - (43%)
• Gaps: 37/310 - (11%)

  Fly   109 LIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKSGQSKGFGFVRFGSYDAQMRVLTNR-HLID 172
            |.:.||.::|||:|||.:||.:|::....:.:|..:.:|:|||||.:.|.......:|.| |.:|
Zfish    15 LFIGGLSFETTEDSLRAHFEQWGKLTDCVVMRDPANKRSRGFGFVTYSSVSEVDAAMTARPHKVD 79

  Fly   173 GRWCEVK-----VPNSKGMGHQVPCKVFVGRCTEDINSDDLREYFSKFG--EVTDVFIPRPF--- 227
            ||..|.|     ..::|...|....|:|||...||.....:||||..:|  |..|:...|..
Zfish    80 GRVVEPKRAVSREDSNKPGAHLTVKKIFVGGIKEDTEEYHIREYFECYGKIETIDIMEERSTGKK 144

  Fly   228 RAFSFVTFLDPDVAQSLCGED-HIIKGVSVHVSNAAPKAEQNRNQQVQSYNYNSANSFGMHSYHP 291
            |.|.||||.|.|....:..:. |.|...:..|..|.||.|...:.. |.|......:|....
Zfish   145 RGFCFVTFDDHDTVDKIVAQKYHTINSHNCEVRKALPKQEMQSSSN-QRYRGGGGGNFTGRG--- 205

  Fly   292 QGNHMNPGRNGHHRGNNQHNAHGGENAIVPNNHNIGTAGYGMGGNNYGGNSGGG-------YH-- 347
             ||....|..|...|.:.:|..||.....|..:..|..||| ||..||...|||       |:
Zfish   206 -GNFGRGGYGGGRGGGDGYNGFGGNYGGGPGGYGGGRGGYG-GGPGYGNQGGGGGFGGFDNYNDR 268

  Fly   348 -NNGGNHSSGGNTNRQDGGSQYN------SRQSNFHGMNQPHNGNVGGSN 390
             |.|||...||.::...||..||      .:||||..|.   ..|.||.|
Zfish   269 GNFGGNFGGGGGSSGGGGGGNYNDFGNYGGQQSNFGPMK---GNNFGGRN 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	28/77 (36%)
		RRM2_TDP43	192..261	CDD:409761	25/74 (34%)
hnrnpa3	NP_001315077.1	RRM1_hnRNPA_like	14..91	CDD:409992	28/75 (37%)
		RRM2_hnRNPA3	104..183	CDD:409996	27/78 (35%)
		HnRNPA1	292..>315	CDD:463312	8/25 (32%)