Protein Alignment TBPH and RBM23

DIOPT Version :10

• Sequence 1: NP_477400.1
• Gene: TBPH / 37781
• FlyBaseID: FBgn0025790
• Length: 531
• Species: Drosophila melanogaster
• Sequence 2: NP_001339693.1
• Gene: RBM23 / 55147
• HGNCID: 20155
• Length: 483
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 55/245 - (22%)
• Similarity: 97/245 - (39%)
• Gaps: 49/245 - (20%)

  Fly    31 QAQFPG-SCGLKYRNLDTKAVRGVRSNEGR-------LFPP---SVESGWGEYAYFCVFPKENKR 84
            :::.|| .|..:.|:.|.:.....||.:.|       ..||   ....|..:..:|  ..|...|
Human   134 RSRSPGRQCRHRSRSWDRRHGSESRSRDHRREDRVHYRSPPLATGYRYGHSKSPHF--REKSPVR 196

  Fly    85 KSDDNL--ENSTAKT---KRIETRLRCTDLIVLGLPWKTTEESLREYFETYGEVLMAQIKKDTKS 144
            :..|||  |...|:|   .::..|:|..|              |.::|...|:|...:|..|..|
Human   197 EPVDNLSPEERDARTVFCMQLAARIRPRD--------------LEDFFSAVGKVRDVRIISDRNS 247

  Fly   145 GQSKGFGFVRFGSYDA--------QMRVLTNRHLIDGRWCE----VKVPNSKGMGHQVPCKVFVG 197
            .:|||..:|.|....:        ..|:|....::.....|    ..:.|:...|:..|.:::||
Human   248 RRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVG 312

  Fly   198 RCTEDINSDDLREYFSKFGEVTDVFIPRP-----FRAFSFVTFLDPDVAQ 242
            ....:|..|.||..|..||::.::.:.:.     .:.:.|:||.|.:.|:
Human   313 SLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECAR 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBPH	NP_477400.1	TDP43_N	3..78	CDD:465833	12/57 (21%)
		RRM1_TDP43	108..181	CDD:409760	16/84 (19%)
		RRM2_TDP43	192..261	CDD:409761	14/56 (25%)
RBM23	NP_001339693.1	SF-CC1	143..482	CDD:273721	52/236 (22%)